Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 10/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSH | P09668 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164559 | 0.78 | CTSK (0.38) | CTSKCTSLCTSBCTSSCTSD | |
| SCHEMBL5164561 | 0.78 | CTSK (0.38) | CTSKCTSLCTSBCTSSCTSD | |
| SCHEMBL21996681 | 0.78 | GPR119 (0.41) | ACHE | |
| SCHEMBL771696 | 0.77 | ACHE (0.36) | ACHEMEN1KMT2A | |
| SCHEMBL27374399 | 0.76 | HTR2C (0.37) | ACHEALDH1A1KMT2A | |
| SCHEMBL5025593 | 0.74 | NR1H2 (0.42) | ACHEALDH1A1KMT2A | |
| SCHEMBL6018374 | 0.74 | LSS (0.36) | ACHEALDH1A1KMT2A | |
| SCHEMBL6018377 | 0.74 | LSS (0.36) | ACHEALDH1A1KMT2A | |
| SCHEMBL5025592 | 0.74 | NR1H2 (0.42) | ACHEALDH1A1KMT2A | |
| SCHEMBL22755466 | 0.73 | CTSK (0.61) | CTSKCTSLCTSBUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |