Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749932 | 0.88 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL5773385 | 0.82 | RIOK2 (0.48) | KMT2AMEN1RAB9APOLBMAPK10 | |
| SCHEMBL5776205 | 0.81 | KMT2A (0.61) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL5768061 | 0.80 | KMT2A (0.52) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL5780372 | 0.80 | MAPK10 (0.41) | KMT2AMEN1RAB9APOLBMAPK10 | |
| SCHEMBL5748311 | 0.78 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL5776450 | 0.78 | MAPK10 (0.40) | KMT2AMEN1RAB9APOLBMAPK10 | |
| SCHEMBL5775211 | 0.76 | MAPK10 (0.38) | MAPK10MAPK8RIOK2 | |
| SCHEMBL5769845 | 0.76 | MAPK10 (0.38) | MAPK10MAPK8RIOK2 | |
| SCHEMBL5774799 | 0.76 | MAPK10 (0.38) | MAPK10MAPK8RIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |