Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 6/20 | 0.41 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776450 | 0.93 | MAPK10 (0.40) | MAPK10RIOK2GPR52KMT2AGAA | |
| SCHEMBL5769845 | 0.90 | MAPK10 (0.38) | MAPK10RIOK2MAPTKDM4E | |
| SCHEMBL5774799 | 0.90 | MAPK10 (0.38) | MAPK10RIOK2MAPTKDM4E | |
| SCHEMBL5775211 | 0.90 | MAPK10 (0.38) | MAPK10RIOK2MAPTKDM4E | |
| SCHEMBL5773385 | 0.90 | RIOK2 (0.48) | MAPK10RIOK2GPR52KMT2AGAA | |
| SCHEMBL5770617 | 0.83 | RIOK2 (0.38) | MAPK10RIOK2KMT2AGAAMAPT | |
| SCHEMBL5750843 | 0.81 | ALDH1A1 (0.39) | MAPK10RIOK2GPR52KMT2AMAPT | |
| SCHEMBL5750867 | 0.80 | TRPV1 (0.41) | MAPK10KMT2AMAPTMEN1KDM4E | |
| SCHEMBL5778360 | 0.80 | KMT2A (0.49) | MAPK10RIOK2KMT2AMEN1POLB | |
| SCHEMBL5778696 | 0.79 | RIOK2 (0.45) | MAPK10RIOK2KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |