Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904435 | 0.84 | KMT2A (0.68) | KMT2AMEN1MAPK10GFERAPAF1 | |
| SCHEMBL5778360 | 0.81 | KMT2A (0.49) | KMT2AMEN1MAPK10NPC1RAB9A | |
| SCHEMBL5770714 | 0.81 | KMT2A (0.50) | KMT2AMEN1MAPK10GFERAPAF1 | |
| SCHEMBL3972303 | 0.80 | ALDH1A1 (0.58) | KMT2AMEN1CDC25BKDM4ESMN1; SMN2 | |
| SCHEMBL31346513 | 0.80 | ALDH1A1 (0.58) | KMT2AMEN1CDC25BKDM4ESMN1; SMN2 | |
| SCHEMBL5772903 | 0.80 | KMT2A (0.51) | KMT2AMEN1MAPK10GFERAPAF1 | |
| SCHEMBL5773385 | 0.78 | RIOK2 (0.48) | KMT2AMEN1MAPK10GFERRCE1 | |
| SCHEMBL13367472 | 0.78 | KMT2A (0.58) | KMT2AMEN1MAPK10GFERAPAF1 | |
| SCHEMBL6542106 | 0.78 | ALDH1A1 (0.56) | KMT2AMEN1CDC25BKDM4ESMN1; SMN2 | |
| SCHEMBL3279571 | 0.78 | MEN1 (1.00) | KMT2AMEN1MAPK10GFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |