Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780372 | 0.90 | MAPK10 (0.41) | RIOK2MAPK10KMT2AMEN1GPR52 | |
| SCHEMBL5776450 | 0.87 | MAPK10 (0.40) | RIOK2MAPK10KMT2AMEN1GPR52 | |
| SCHEMBL5775211 | 0.85 | MAPK10 (0.38) | RIOK2MAPK10MAPTKDM4E | |
| SCHEMBL5769845 | 0.85 | MAPK10 (0.38) | RIOK2MAPK10MAPTKDM4E | |
| SCHEMBL5774799 | 0.85 | MAPK10 (0.38) | RIOK2MAPK10MAPTKDM4E | |
| SCHEMBL5775894 | 0.82 | RIOK2 (0.48) | RIOK2MAPK10NOS3NOS1NOS2 | |
| SCHEMBL5778360 | 0.82 | KMT2A (0.49) | RIOK2MAPK10NOS2KMT2AMEN1 | |
| SCHEMBL5748108 | 0.80 | RIOK2 (0.44) | RIOK2MAPK10NOS3NOS1NOS2 | |
| SCHEMBL5776205 | 0.78 | KMT2A (0.61) | MAPK10KMT2AMEN1GAAMAPT | |
| SCHEMBL5771765 | 0.78 | RIOK2 (0.56) | RIOK2MAPK10NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |