SCHEMBL577838

SCHEMBL577838

Fc1ccc(Br)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.41
KCNH2 Q12809 4/20 0.41
KDM1B Q8NB78 3/20 0.41
CES2 O00748 2/20 0.40
CES1 P23141 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29544666 1.00 KDM1A (0.41) KDM1AKCNH2KDM1BCES2CES1
SCHEMBL29666934 0.87 KDM1A (0.48) KDM1AKCNH2KDM1B
SCHEMBL855230 0.87 KDM1A (0.48) KDM1AKCNH2KDM1B
SCHEMBL13738335 0.85 KDM1A (0.34) KDM1AKCNH2KDM1BCES2CES1
Hydrochloric Acid SCHEMBL16178512 0.83 KDM1A (0.33) KDM1AKCNH2KDM1BCES2CES1
SCHEMBL8049727 0.82 KDM1A (0.32) KDM1AKCNH2KDM1BCES2CES1
SCHEMBL29489580 0.79 CES2 (0.53) CES2CES1
SCHEMBL45430 0.79 CES2 (0.53) CES2CES1
SCHEMBL246708 0.79 CES2 (0.39) KDM1AKCNH2KDM1BCES2CES1
SCHEMBL29365299 0.79 KDM1A (0.35) KDM1AKCNH2KDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-221733336-U Equipment is used in trifluoro bromobenzene production 科莱博(江苏)科技股份有限公司 2024-09-20 CN claimed
CN-219483685-U Cleaning liquid pipe of trifluoro bromobenzene apparatus for producing 浙江解氏新材料股份有限公司 2023-08-08 CN claimed
CN-216572982-U Trifluoro bromobenzene production device 宿迁市科莱博生物化学有限公司 2022-05-24 CN claimed
EP-3543319-A1 METHOD OF MARKING HYDROCARBON LIQUIDS Johnson Matthey Public Limited Company (GB) 2019-09-25 EP claimed
CN-107383418-B A kind of uvioresistant plastic additive and preparation method thereof 广东宝利兴科技有限公司 2019-05-17 CN claimed
CN-107673951-A A kind of high efficiency preparation method of 2,4,5 trifluoro benzene acetic acid 河南师范大学 2018-02-09 CN claimed
CN-107383418-A A kind of unioresistant plastic additive and preparation method thereof 侯茜茜 2017-11-24 CN claimed
CN-105439810-B Preparation method of 3,4,5-trifluorobromobenzene 浙江永太科技股份有限公司 2017-04-12 CN claimed
CN-104610016-B A kind of preparation method of 3,4,5-trifluorobromobenzene compound 浙江永太科技股份有限公司 2016-06-22 CN claimed
EP-2197829-B1 ARYLAMINE SYNTHESIS METHOD CENTRE NAT RECH SCIENT (FR) 2016-05-04 EP claimed
CN-1358708-A Method for synthesizing 2,3,4-trifluoro phenyl formic acid SHANGHAI INST ORGANIC CHEM (CN) 2002-07-17 CN claimed
WO-2001058834-A1 METHOD FOR PREPARING A POLYAROMATIC COMPOUND RHODIA CHIMIE (FR) 2001-08-16 WO claimed
EP-0667328-B1 Process for the preparation of aromatic fluoro compounds CLARIANT GMBH (DE) 1998-09-16 EP claimed
US-5498807-A Process for the preparation of aromatic fluoro compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-03-12 US claimed
EP-0667328-A1 Process for the preparation of aromatic fluoro compounds HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-16 EP claimed
EP-0488861-A1 Process for the preparation of alkoxylated aromatic compounds RHONE-POULENC CHIMIE (FR) 1992-06-03 EP claimed
EP-0455545-A1 Process for the preparation of mono- or polyalkoxylated aromatic compounds RHONE-POULENC CHIMIE (FR) 1991-11-06 EP claimed
EP-0434516-A2 Process for the preparation of mono- or poly-alkoxylated aromatic compounds RHONE-POULENC CHIMIE (FR) 1991-06-26 EP claimed
EP-0434517-A2 Process for the preparation of mono- or poly-alkoxylated aromatic compounds RHONE-POULENC CHIMIE (FR) 1991-06-26 EP claimed
US-4479022-A ETHER, ALKALINE BASE CATALYST COMPLEXES RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-10-23 US claimed