Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782107 | 0.92 | PRKCI (0.65) | PRKCI | |
| SCHEMBL7513676 | 0.91 | PRKCI (0.59) | PRKCI | |
| SCHEMBL5780971 | 0.90 | KDM4E (0.54) | PRKCI | |
| SCHEMBL5782433 | 0.89 | PRKCI (0.66) | PRKCI | |
| SCHEMBL8172960 | 0.88 | LMNA (0.49) | PRKCI | |
| SCHEMBL7015020 | 0.88 | PTGS2 (0.51) | PRKCI | |
| SCHEMBL6707189 | 0.88 | PDE4B (0.51) | PRKCI | |
| SCHEMBL7169369 | 0.87 | KDM4E (0.51) | PRKCI | |
| SCHEMBL5780526 | 0.86 | PRKCI (0.49) | PRKCI | |
| SCHEMBL7404512 | 0.86 | MAPT (0.53) | PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685136-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047292-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 2005-05-26 | — | — | WO | disclosed |
| US-6110920-A | TREATMENT OF CARDIOVASCULAR DISORDERS AND IMPOTENCY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-08-29 | — | — | US | disclosed |
| EP-0920431-A1 | THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006722-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |