Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Methyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL9751217 | 0.91 | TSHR (0.50) | — | |
| Methyl Alcohol SCHEMBL11122748 | 0.80 | — | — | |
| Methyl Alcohol SCHEMBL9192624 | 0.80 | — | — | |
| Methyl Alcohol SCHEMBL28269823 | 0.80 | — | — | |
| Methyl Alcohol SCHEMBL10666229 | 0.80 | — | — | |
| Methyl Alcohol SCHEMBL28910759 | 0.80 | — | — | |
| Methyl Alcohol SCHEMBL9421550 | 0.80 | — | — | |
| Methyl Alcohol SCHEMBL3628465 | 0.80 | — | — | |
| Methyl Alcohol SCHEMBL118068 | 0.80 | — | — | |
| Methyl Alcohol SCHEMBL28286313 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116112-B | Preparation method of in-situ soil brick and application of in-situ soil brick prepared by method | 宁波财经学院 | 2022-04-15 | — | — | CN | claimed |
| CN-110157200-B | Pigment layer reinforcing agent based on modified bone glue | 陕西师范大学 | 2021-04-20 | — | — | CN | claimed |
| CN-108383723-B | Preparation method of beta-methyl glutarate monomethyl ester with high purity and high yield | 淄博职业学院 | 2021-03-23 | — | — | CN | claimed |
| CN-111116112-A | Preparation method of in-situ soil brick and application of in-situ soil brick prepared by method | 宁波财经学院 | 2020-05-08 | — | — | CN | claimed |
| CN-110157200-A | A kind of coat of colo(u)r strengthening agent based on Modify bone glue | 陕西师范大学 | 2019-08-23 | — | — | CN | claimed |
| CN-109746202-A | A kind of archives wisdom cleaning deacidification disinfection protection method | 安徽爱吉泰克科技有限公司 | 2019-05-14 | — | — | CN | claimed |
| CN-105733601-B | Earthen site weathering prevention reinforcing agent and reinforcing method | 陕西师范大学 | 2019-04-12 | — | — | CN | claimed |
| CN-108383723-A | The preparation method of high-purity, high yield Beta-methyl monomethyl glutarate | 淄博职业学院 | 2018-08-10 | — | — | CN | claimed |
| CN-105733601-A | Earthen site weathering prevention reinforcing agent and reinforcing method | 陕西师范大学 | 2016-07-06 | — | — | CN | claimed |
| CN-108914701-B | Can be used to whole volume ancient book deacidification reinforcing and fixing device in batches | 华南理工大学 | 2023-06-20 | — | — | CN | disclosed |
| US-11549218-B2 | Device for deacidifying, reinforcing and strengthening ancient books | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2023-01-10 | — | — | US | disclosed |
| CN-107881850-B | Ancient book deacidification reinforcing and strengthening device | 华南理工大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-111116112-B | Preparation method of in-situ soil brick and application of in-situ soil brick prepared by method | 宁波财经学院 | 2022-04-15 | — | — | CN | disclosed |
| CN-111116112-B | Preparation method of in-situ soil brick and application of in-situ soil brick prepared by method | 宁波财经学院 | 2022-04-15 | — | — | CN | disclosed |
| US-20050032847-A1 | 2-amino-6(2,4,5-substitued-phenyl)-pyridines | PFIZER INC. | 2005-02-10 | — | — | US | disclosed |
| US-6803470-B2 | NITRIC OXIDE SYNTHASE INHIBITORS. | PFIZER INC | 2004-10-12 | — | — | US | disclosed |
| EP-1434624-A1 | 2-AMINO-6-(2,4,5-SUBSTITUTED-PHENYL)-PYRIDINES FOR USE AS NITRIC OXIDE SYNTHASE INHIBITORS | Pfizer Products Inc. (US) | 2004-07-07 | — | — | EP | disclosed |
| US-20040077853-A1 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines | PFIZER INC. | 2004-04-22 | — | — | US | disclosed |
| US-20030087891-A1 | 2-Amino-6-(2,4,5-substituted-phenyl)-pyridines | PFIZER INC. | 2003-05-08 | — | — | US | disclosed |
| WO-2003030993-A1 | 2-AMINO-6-(2,4,5-SUBSTITUTED-PHENYL)-PYRIDINES FOR USE AS NITRIC OXIDE SYNTHASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-04-17 | — | — | WO | disclosed |