Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | GLA | P06280 | 6/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | GAA | P10253 | 8/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17750396 | 0.84 | ALDH1A1 (0.75) | RAB9AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL1494735 | 0.83 | RAB9A (1.00) | RAB9AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL17750400 | 0.82 | KDM4E (0.84) | RAB9AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL17750391 | 0.82 | RAB9A (0.84) | RAB9AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL5305847 | 0.81 | ALDH1A1 (0.76) | RAB9AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL3671367 | 0.81 | ALDH1A1 (1.00) | RAB9AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL971743 | 0.80 | ALDH1A1 (1.00) | RAB9AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL1692157 | 0.80 | ALDH1A1 (1.00) | RAB9AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL14646388 | 0.80 | ALDH1A1 (0.73) | RAB9AKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL12970202 | 0.80 | ALDH1A1 (0.73) | RAB9AKMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | RAB9A 3127/4885KMT2A 3533/4885ALDH1A1 1541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.