Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778916 | 0.85 | DCPS (0.36) | — | |
| Oxalic Acid SCHEMBL5781174 | 0.81 | MEN1 (0.39) | — | |
| SCHEMBL5779801 | 0.80 | HPGD (0.42) | GRM2PARP15PARP10HPGD | |
| SCHEMBL5782831 | 0.79 | HTR2A (0.52) | SIGMAR1 | |
| SCHEMBL5777663 | 0.79 | CXCR4 (0.43) | — | |
| SCHEMBL5781110 | 0.76 | KCNH2 (0.43) | — | |
| Oxalic Acid SCHEMBL5778829 | 0.75 | MEN1 (0.46) | — | |
| SCHEMBL5779854 | 0.75 | MEN1 (0.45) | — | |
| SCHEMBL5784012 | 0.74 | MAPT (0.40) | — | |
| SCHEMBL5780290 | 0.74 | KCNH2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254904-B1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | EISAI CO LTD (JP) | 2006-05-24 | — | — | EP | claimed |