Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29748966 | 0.80 | KCNH2 (0.39) | ALDH1A1MAPTMEN1KMT2AL3MBTL3 | |
| SCHEMBL23884703 | 0.77 | MAPT (0.58) | ALDH1A3ALDH1A1ALDH3A1SMN1; SMN2MAPT | |
| SCHEMBL249009 | 0.76 | TRIM24 (0.58) | ALDH1A1SMN1; SMN2MAPTL3MBTL3TRIM24 | |
| SCHEMBL29748887 | 0.76 | LCK (0.43) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL28799317 | 0.75 | TNIK (0.44) | ALDH1A1SMN1; SMN2MAPTPDCD1CD274 | |
| SCHEMBL29748892 | 0.74 | PDCD1 (0.41) | MEN1GAAKMT2AL3MBTL3PIM1 | |
| SCHEMBL23048797 | 0.72 | OPRD1 (0.46) | L3MBTL3 | |
| SCHEMBL2423035 | 0.72 | PIM1 (0.50) | MEN1GAAKMT2AL3MBTL3PIM1 | |
| SCHEMBL5776815 | 0.71 | ALDH1A3 (0.49) | ALDH1A3ALDH1A1ALDH3A1SMN1; SMN2MAPT | |
| SCHEMBL13538106 | 0.71 | PIM1 (0.45) | ALDH1A1PIM1PIM3PIM2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | ALDH1A3 3528/4885ALDH1A1 1541/4885ALDH3A1 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.