Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212190 | 0.84 | ALDH1A3 (0.46) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4138974 | 0.82 | ALDH1A1 (0.68) | ALDH1A3ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL19212321 | 0.79 | ALDH1A3 (0.46) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30501279 | 0.79 | ALDH1A1 (0.44) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4756395 | 0.74 | TRIM24 (0.61) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL103066 | 0.73 | NPC1 (0.53) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL5779339 | 0.71 | ALDH1A3 (0.47) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17422299 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2AHTTL3MBTL1 | |
| SCHEMBL23777678 | 0.70 | AKR1C3 (0.66) | ALDH1A1KMT2AMEN1AKR1C3 | |
| SCHEMBL17479168 | 0.69 | ALDH1A3 (0.63) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | ALDH1A3 3528/4885ALDH3A1 1650/4885ALDH1A1 1541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.