Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5912950 | 0.81 | ABCB1 (0.36) | NSD2SETDB1 | |
| SCHEMBL5110282 | 0.79 | HTT (0.50) | NSD2SIGMAR1TMEM97NPC1POLB | |
| SCHEMBL5114431 | 0.79 | FFAR1 (0.48) | NSD2MAP2K1 | |
| SCHEMBL5118098 | 0.76 | NSD2 (0.63) | NSD2SIGMAR1TMEM97KMT2AMEN1 | |
| SCHEMBL31721449 | 0.76 | CYP2A6 (0.47) | SETDB1KMT2AMEN1TTRALB | |
| SCHEMBL399126 | 0.76 | CYP2A6 (0.47) | SETDB1KMT2AMEN1TTRALB | |
| SCHEMBL5779948 | 0.75 | ALDH1A1 (0.33) | KMT2AMEN1NPC1 | |
| SCHEMBL5912952 | 0.74 | SETDB1 (0.34) | SIGMAR1TMEM97SETDB1KMT2AMEN1 | |
| SCHEMBL17629902 | 0.74 | FFAR1 (0.51) | NPSR1MMP2 | |
| SCHEMBL12505597 | 0.73 | MEP1A (0.56) | NSD2KMT2AMEN1NPC1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |