Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17629998 | 0.92 | NAMPT (0.42) | SETDB1NOS3NOS1NOS2CDK2 | |
| SCHEMBL17629872 | 0.85 | HSD17B10 (0.44) | SETDB1NOS3NOS1NOS2KMT2A | |
| SCHEMBL17629902 | 0.80 | FFAR1 (0.51) | FFAR1FFAR4 | |
| SCHEMBL5114440 | 0.79 | FFAR1 (0.54) | ABCB1HPGDABCG2FFAR1FFAR4 | |
| SCHEMBL5110287 | 0.79 | P2RX7 (0.46) | MAPTABCB1HPGDABCG2CNR1 | |
| SCHEMBL17672564 | 0.78 | FFAR1 (0.46) | SMN1; SMN2FFAR1FFAR4 | |
| SCHEMBL17629879 | 0.77 | KMT2A (0.48) | SETDB1KMT2AMEN1NAMPT | |
| SCHEMBL17672822 | 0.76 | SETDB1 (0.40) | SETDB1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL3896082 | 0.76 | MMP3 (0.44) | SETDB1KMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL17629927 | 0.76 | FFAR1 (0.38) | SETDB1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |