Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | CCNK | O75909 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCND3 | P30281 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941542 | 0.82 | MAPK10 (0.73) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL31220877 | 0.82 | MAPK10 (0.73) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL20194777 | 0.81 | MEN1 (0.61) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL16089597 | 0.79 | MAPK10 (0.58) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL18199830 | 0.78 | MEN1 (0.67) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL12886656 | 0.78 | MAPK10 (0.56) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL18880494 | 0.78 | MEN1 (0.56) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL23319534 | 0.77 | MEN1 (0.60) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL8686406 | 0.76 | MAPK10 (0.58) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL12887517 | 0.76 | MEN1 (0.53) | MAPK10MEN1KMT2AGFERKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |