SCHEMBL18199830

SCHEMBL18199830

Cc1cc(Nc2ccccn2)c(Nc2ccccn2)cc1C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.67
KMT2A Q03164 4/20 0.67
MAPK10 P53779 2/20 0.67
GFER P55789 1/20 0.67
KDR P35968 1/20 0.50
RAB9A P51151 6/20 0.47
NPSR1 Q6W5P4 3/20 0.47
NPC1 O15118 6/20 0.47
MAPT P10636 2/20 0.46
CCNK O75909 1/20 0.46
CCNA2 P20248 1/20 0.46
CDK2 P24941 1/20 0.46
CCND3 P30281 1/20 0.46
CDK9 P50750 1/20 0.46
CDK6 Q00534 1/20 0.46
THRB P10828 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GRM5 P41594 1/20 0.44
ADRA2A P08913 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31220877 0.84 MAPK10 (0.73) MEN1KMT2AMAPK10GFERKDR
SCHEMBL7941542 0.84 MAPK10 (0.73) MEN1KMT2AMAPK10GFERKDR
SCHEMBL3279571 0.81 MEN1 (1.00) MEN1KMT2AMAPK10GFERKDR
SCHEMBL24237479 0.80 MEN1 (0.56) MEN1KMT2AMAPK10GFERKDR
SCHEMBL12886656 0.80 MAPK10 (0.56) MEN1KMT2AMAPK10GFERKDR
SCHEMBL18199868 0.80 MEN1 (0.44) MEN1KMT2AMAPK10GFERKDR
SCHEMBL25175479 0.79 RAB9A (0.63) MEN1KMT2AMAPK10GFERKDR
SCHEMBL5914015 0.79 KMT2A (0.55) MEN1KMT2AMAPK10GFERKDR
SCHEMBL4033484 0.79 MAPK10 (0.55) MEN1KMT2AMAPK10GFERKDR
SCHEMBL5771649 0.78 MAPK10 (0.70) MEN1KMT2AMAPK10GFERKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
WO-2016174813-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING HETEROMONOCYCLIC GROUPS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT AND DISPLAY DEVICE CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2016-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 MEN1 2142/4885KMT2A 2024/4885MAPK10 3598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.