Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
| ▸ | DHPS | P49366 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779427 | 0.91 | TRPV1 (0.35) | TRPV1METTL3DHPSRAF1BRAF | |
| SCHEMBL5774468 | 0.84 | TRPV1 (0.33) | TRPV1DHPS | |
| SCHEMBL5779746 | 0.82 | NR3C1 (0.41) | TRPV1METTL3DHPSRAF1BRAF | |
| SCHEMBL5774962 | 0.76 | NR3C1 (0.46) | TRPV1METTL3RAF1BRAF | |
| SCHEMBL5779425 | 0.74 | NR3C1 (0.43) | TRPV1METTL3DHPSRAF1BRAF | |
| SCHEMBL5775583 | 0.72 | NR3C1 (0.40) | — | |
| SCHEMBL5798295 | 0.67 | NR3C1 (0.48) | TRPV1METTL3RAF1BRAF | |
| SCHEMBL5774465 | 0.66 | NR3C1 (0.46) | TRPV1DHPS | |
| SCHEMBL6411423 | 0.65 | NR3C1 (0.46) | TRPV1DHPSRAF1BRAF | |
| SCHEMBL6404831 | 0.64 | NR3C1 (0.52) | TRPV1RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638945-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Schering Aktiengesellschaft (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005003098-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | WO | disclosed |