Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.58 |
| ▸ | PDE10A | Q9Y233 | 15/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779899 | 0.86 | TRPV3 (0.45) | TRPV3PDE10A | |
| SCHEMBL10233469 | 0.81 | PDE10A (0.57) | TRPV3PDE10AHCRTR1HCRTR2 | |
| SCHEMBL14818715 | 0.80 | PDE10A (0.59) | TRPV3PDE10A | |
| SCHEMBL23207442 | 0.78 | PDE10A (0.54) | TRPV3PDE10AHCRTR1HCRTR2 | |
| SCHEMBL20548111 | 0.78 | PDE10A (0.54) | TRPV3PDE10AHCRTR1HCRTR2 | |
| SCHEMBL15537495 | 0.78 | TRPV3 (0.58) | TRPV3PDE10AHCRTR1HCRTR2 | |
| SCHEMBL12088749 | 0.77 | TRPV3 (0.55) | TRPV3PDE10A | |
| Hydrochloric Acid SCHEMBL23167793 | 0.77 | PDE10A (0.52) | TRPV3PDE10AHCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL30152537 | 0.77 | PDE10A (0.52) | TRPV3PDE10AHCRTR1HCRTR2 | |
| SCHEMBL6242988 | 0.76 | HSD11B1 (0.50) | TRPV3PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154291-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |