Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 12/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.38 |
| ▸ | HTR3B | O95264 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779904 | 0.86 | TRPV3 (0.58) | TRPV3PDE10A | |
| SCHEMBL5779772 | 0.74 | HRH3 (0.43) | TRPV3PDE10AHRH3 | |
| SCHEMBL3625374 | 0.73 | GABRA1 (0.44) | — | |
| SCHEMBL2965375 | 0.72 | NOS3 (0.35) | TRPV3PDE10A | |
| SCHEMBL30464666 | 0.72 | NOS3 (0.35) | TRPV3PDE10A | |
| SCHEMBL28876577 | 0.69 | GRIN2D (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13362485 | 0.68 | PDE10A (0.55) | TRPV3PDE10AHTR3EHTR3BHTR3A | |
| SCHEMBL14818715 | 0.68 | PDE10A (0.59) | TRPV3PDE10A | |
| SCHEMBL10233469 | 0.67 | PDE10A (0.57) | TRPV3PDE10A | |
| SCHEMBL12088749 | 0.67 | TRPV3 (0.55) | TRPV3PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |