Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166146 | 0.85 | ACACB (0.54) | ALDH1A1KDM4ERAB9ANPC1ACACB | |
| SCHEMBL2099046 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4ETSHRRAB9ANPC1 | |
| SCHEMBL21384883 | 0.83 | TSHR (0.42) | ALDH1A1KDM4ETSHRRAB9ANPC1 | |
| SCHEMBL3633272 | 0.80 | DAO (0.42) | ALDH1A1RAB9ANPC1ACACB | |
| SCHEMBL21327591 | 0.79 | RAB9A (0.46) | ALDH1A1TSHRRAB9ANPC1FPR2 | |
| SCHEMBL21327423 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRRAB9ANPC1 | |
| SCHEMBL13607699 | 0.78 | CPB2 (0.44) | ALDH1A1RAB9ANPC1ACACBFPR2 | |
| SCHEMBL2846343 | 0.78 | HIF1A (0.56) | ALDH1A1RAB9ANPC1POLBLMNA | |
| SCHEMBL2886185 | 0.77 | RAB9A (0.36) | ALDH1A1KDM4ETSHRRAB9ANPC1 | |
| SCHEMBL3515895 | 0.77 | FFAR1 (0.55) | ALDH1A1KDM4ETSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560488-A4 | ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2006-08-02 | — | — | EP | disclosed |
| EP-1560488-A2 | ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041210-A2 | ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-21 | — | — | WO | disclosed |