Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.30 |
| ▸ | ABAT | P80404 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780065 | 0.84 | TYR (0.44) | TYRADRB2ADRB1ADRB3ALDH1A3 | |
| SCHEMBL2065202 | 0.73 | TYR (0.48) | TYRADRB2ADRB1ADRB3ALDH1A3 | |
| SCHEMBL6665120 | 0.71 | ADRB2 (0.37) | TYRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL7546488 | 0.71 | CYP2A6 (0.46) | ADRB2ADRB1ADRB3ALDH1A3ALDH1A1 | |
| SCHEMBL16569010 | 0.71 | TYR (0.46) | TYRADRB2ADRB1ADRB3ALDH1A3 | |
| SCHEMBL3261042 | 0.70 | CYP2A6 (0.48) | ALDH1A3ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL14831224 | 0.70 | CTSK (0.45) | TYRALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL14831223 | 0.70 | CTSK (0.45) | TYRALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL24528858 | 0.69 | BCL2A1 (0.39) | TYRADRB2ADRB1ADRB3ALDH1A3 | |
| SCHEMBL2197875 | 0.69 | TYR (0.47) | TYRADRB2ADRB1ADRB3ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | TYR 650/4885ADRB2 339/4885ADRB1 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.