Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533342 | 1.00 | ATM (0.50) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL3289149 | 1.00 | ATM (0.50) | ATMCTSSCTSKCTSLCTSB | |
| Methylamine SCHEMBL5634041 | 0.98 | ATM (0.48) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL5780052 | 0.89 | CTSK (0.50) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL8082012 | 0.88 | ATM (0.56) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL1624127 | 0.82 | SMYD3 (0.42) | — | |
| SCHEMBL1624124 | 0.82 | SMYD3 (0.42) | — | |
| SCHEMBL4715527 | 0.81 | SMYD3 (0.46) | CTSSCTSKAKT1 | |
| SCHEMBL4715530 | 0.81 | SMYD3 (0.46) | CTSSCTSKAKT1 | |
| SCHEMBL8504093 | 0.81 | CTSK (0.44) | ATMCTSSCTSKCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |