SCHEMBL578030

SCHEMBL578030

COc1ccc(NCl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.64
RAB9A P51151 4/20 0.64
GAA P10253 3/20 0.64
NPC1 O15118 3/20 0.64
MAPK1 P28482 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
KDM4E B2RXH2 1/20 0.64
THRB P10828 1/20 0.64
RECQL P46063 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CA1 P00915 3/20 0.58
CA2 P00918 3/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ALDH1A1 P00352 2/20 0.56
HTT P42858 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31565002 0.91 MAPT (0.54) MAPTRAB9AGAANPC1MAPK1
SCHEMBL8359254 0.80 MAPT (0.58) MAPTRAB9AGAANPC1MAPK1
Bromide SCHEMBL28373773 0.78 MAPT (0.56) MAPTRAB9AGAANPC1MAPK1
Hydrochloric Acid SCHEMBL28375387 0.78 MAPT (0.56) MAPTRAB9AGAANPC1MAPK1
Water SCHEMBL10563582 0.78 GAA (0.56) MAPTRAB9AGAANPC1MAPK1
SCHEMBL851498 0.78 RAB9A (0.70) MAPTRAB9AGAANPC1MAPK1
SCHEMBL1459772 0.78 MAPT (1.00) MAPTRAB9AGAANPC1MAPK1
SCHEMBL39057 0.78 MAPT (1.00) MAPTRAB9AGAANPC1MAPK1
SCHEMBL23270081 0.77 CYP1A2 (0.55) MAPTRAB9AGAANPC1MAPK1
1,4-Dimethoxybenzene SCHEMBL8489 0.76 CA1 (1.00) MAPTRAB9AGAANPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4914213-A Indole derivatives and process for producing the same FUJI PHOTO FILM CO., LTD. (JP) 1990-04-03 US claimed
US-4707553-A Indole derivatives and process for producing the same FUJI PHOTO FILM CO., LTD. (JP) 1987-11-17 US claimed
US-4159264-A Automatic control of azo coupling processes in the manufacture of azo pigments CIBA-GEIGY CORPORATION (US) 1979-06-26 US claimed
EP-4680602-A1 HETEROCYCLIC COMPOUNDS AS SELECTIVE HDAC6 INHIBITORS Miralinc Pharma, Inc. (US) 2026-01-21 EP disclosed
WO-2024192237-A1 HETEROCYCLIC COMPOUNDS AS SELECTIVE HDAC6 INHIBITORS MIRALINC PHARMA, INC. (US) 2024-09-19 WO disclosed
US-20230159476-A1 PROCESS FOR THE SYNTHESIS OF COMPOUNDS WHICH ABSORB ULTRAVIOLET RADIATION IN FLOW CONDITIONS AND FORMULATIONS COMPRISING SAME ELIKIMIA INC (CA) 2023-05-25 US disclosed
US-20230159476-A1 PROCESS FOR THE SYNTHESIS OF COMPOUNDS WHICH ABSORB ULTRAVIOLET RADIATION IN FLOW CONDITIONS AND FORMULATIONS COMPRISING SAME ELIKIMIA INC (CA) 2023-05-25 US disclosed
WO-2023279205-A1 ULTRAVIOLET AND VISIBLE RADIATION ABSORBING COMPOUNDS elkimia inc. (CA) 2023-01-12 WO disclosed
CN-105294732-B Conformationally constrained, fully synthetic macrocyclic compounds 波利弗尔股份公司 2018-09-25 CN disclosed
US-9353100-B2 Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections IDENIX PHARMACEUTICALS LLC (US) 2016-05-31 US disclosed
EP-2461811-B1 MACROCYCLIC SERINE PROTEASE INHIBITORS USEFUL AGAINST VIRAL INFECTIONS, PARTICULARLY HCV IDENIX PHARMACEUTICALS LLC (US) 2016-04-20 EP disclosed
US-4224027-A Process for the production of water-insoluble azo dyestuffs on the fiber with polyphosphate HOECHST AKTIENGESELLSCHAFT (DE) 1980-09-23 US disclosed
US-4183727-A Process for the production of water-insoluble azo dyestuffs on the fiber HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-15 US disclosed
US-4159264-A Automatic control of azo coupling processes in the manufacture of azo pigments CIBA-GEIGY CORPORATION (US) 1979-06-26 US disclosed
US-4115055-A Mixture of water-insoluble monoazo dyestuffs for coloring textile materials consisting at least partly of linear, aromatic polyesters ROHNER AG PRATTELN (CH) 1978-09-19 US disclosed
US-4082503-A PROCESS FOR THE PRODUCTION OF WATER-INSOLUBLE AZO DYESTUFFS ON THE FIBER HOECHST AKTIENGESELLSCHAFT (DT) 1978-04-04 US disclosed
US-4035144-A Dyeing preparations containing boric acid for preparing water-insoluble azo dyestuffs on fiber HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed
US-3960926-A Process for preparing azasulfonium halide salts THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1976-06-01 US disclosed
US-3954797-A Process for preparing azasulfonium halide salts CHROMALLOY AMERICAN CORPORATION (US) 1976-05-04 US disclosed
US-3947515-A Process for the preparation of pure, aromatic o-hydroxy-carboxylic acid aryl amides HOECHST AKTIENGESELLSCHAFT (DT) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159476-A1 PROCESS FOR THE SYNTHESIS OF COMPOUNDS WHICH ABSORB ULTRAVIOLET RADIATION IN FLOW CONDITIONS AND FORMULATIONS COMPRISING SAME ERCC4, XPA, ERCC1 MAPT 358/4885RAB9A 1286/4885GAA 307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.