Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492736 | 0.89 | IDO1 (0.68) | IDO1KMT2AMAOBTAAR1TACR1 | |
| Hydroxyamine SCHEMBL8924228 | 0.83 | IDO1 (0.67) | IDO1KMT2AMAOBTAAR1 | |
| SCHEMBL5782964 | 0.83 | GRIN2B (0.52) | IDO1MAOBAGXTTACR1 | |
| SCHEMBL4995796 | 0.82 | IDO1 (0.64) | IDO1KMT2AMAOBAGXTSLC6A4 | |
| SCHEMBL8076361 | 0.82 | IDO1 (0.59) | IDO1KMT2AMAOBTAAR1TACR1 | |
| SCHEMBL11926053 | 0.81 | P2RX3 (0.50) | IDO1PPARGPPARAMAOBP2RX3 | |
| SCHEMBL8995755 | 0.80 | IDO1 (0.61) | IDO1KMT2AMAOBAGXTSLC6A4 | |
| SCHEMBL668193 | 0.80 | IDO1 (0.57) | IDO1KMT2AMAOBTAAR1TACR1 | |
| SCHEMBL196588 | 0.80 | CYP19A1 (0.55) | KMT2AP2RX3CYP19A1 | |
| SCHEMBL28777340 | 0.80 | CYP19A1 (0.55) | KMT2AP2RX3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620086-A1 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS OF PREPARATION | Warner-Lambert Company LLC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004091604-A1 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS OF PREPARATION | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-28 | — | — | WO | disclosed |