Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 7/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492736 | 0.93 | IDO1 (0.68) | IDO1KMT2AMAOBTAAR1ALDH1A1 | |
| SCHEMBL668193 | 0.83 | IDO1 (0.57) | IDO1KMT2AMAOBTAAR1ALDH1A1 | |
| SCHEMBL5780375 | 0.83 | IDO1 (0.57) | IDO1KMT2AMAOBTAAR1 | |
| SCHEMBL17298962 | 0.83 | MGLL (0.68) | IDO1KMT2AMAOBALDH1A1PTPN2 | |
| SCHEMBL2399721 | 0.83 | TRPV6 (0.68) | IDO1KMT2AMAOBTAAR1ALDH1A1 | |
| SCHEMBL13737507 | 0.82 | IDO1 (0.55) | IDO1KMT2AMAOBTAAR1ALDH1A1 | |
| SCHEMBL28622661 | 0.82 | IDO1 (0.60) | IDO1KMT2AMAOBTAAR1ALDH1A1 | |
| SCHEMBL3434078 | 0.81 | IDO1 (0.59) | IDO1KMT2AMAOBTAAR1ALDH1A1 | |
| SCHEMBL1771605 | 0.81 | IDO1 (0.59) | IDO1KMT2AMAOBTAAR1ALDH1A1 | |
| SCHEMBL29226719 | 0.81 | IDO1 (0.59) | IDO1KMT2AMAOBTAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625067-A | Cyclopentane ether derivatives, processes for their production, and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |