Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492736 | 0.89 | IDO1 (0.68) | IDO1KMT2AMAOBPTPN1PTPN2 | |
| Hydroxyamine SCHEMBL8924228 | 0.83 | IDO1 (0.67) | IDO1KMT2AMAOBPTPN1PTPN2 | |
| SCHEMBL21568941 | 0.83 | MAOB (0.70) | IDO1MAOBPTPN1PTPN2PTPN6 | |
| SCHEMBL9342895 | 0.82 | IDO1 (0.64) | IDO1KMT2AMAOBTAAR1 | |
| SCHEMBL649020 | 0.82 | IDO1 (0.64) | IDO1KMT2AMAOBTAAR1 | |
| SCHEMBL23454355 | 0.82 | ALDH1A1 (0.58) | IDO1KMT2AMAOBPTPN1PTPN2 | |
| SCHEMBL3042346 | 0.81 | SRD5A2 (0.50) | IDO1KMT2AMAOBTAAR1ALDH1A1 | |
| SCHEMBL5780375 | 0.80 | IDO1 (0.57) | IDO1KMT2AMAOBTAAR1TACR1 | |
| SCHEMBL8909 | 0.80 | TRPV1 (0.50) | PTPN1TAAR1ALDH1A1 | |
| SCHEMBL6498113 | 0.79 | SLC6A4 (0.49) | IDO1KMT2APTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758453-B2 | One-component reagent for the fluoroalkylation reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-09-12 | — | — | US | disclosed |
| US-9758453-B2 | One-component reagent for the fluoroalkylation reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-09-12 | — | — | US | disclosed |
| US-20160185691-A1 | One-Component Reagent for the Fluoroalkylation Reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF LLLINOIS (US) | 2016-06-30 | — | — | US | disclosed |
| US-20160185691-A1 | One-Component Reagent for the Fluoroalkylation Reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF LLLINOIS (US) | 2016-06-30 | — | — | US | disclosed |
| US-9193648-B2 | Fluoroalkylation methods and reagents | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-11-24 | — | — | US | disclosed |
| US-9193648-B2 | Fluoroalkylation methods and reagents | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-11-24 | — | — | US | disclosed |
| US-20130225815-A1 | Fluoroalkylation Methods And Reagents | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225815-A1 | Fluoroalkylation Methods And Reagents | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-08-29 | — | — | US | disclosed |
| EP-2606048-A1 | FLUOROALKYLATION METHODS AND REAGENTS | The Board of Trustees of the University of Illinois (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024564-A1 | FLUOROALKYLATION METHODS AND REAGENTS | THE BOARD OF TRUSTESS OF THE UNIVERSITY OF ILLINOIS (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225815-A1 | Fluoroalkylation Methods And Reagents | ALK, AFF4, AFF2 | IDO1 4246/4885KMT2A 1991/4885MAOB 680/4885 |
| US-20160185691-A1 | One-Component Reagent for the Fluoroalkylation Reaction | AOC1, AOC3, AOC2 | IDO1 2884/4885KMT2A 3533/4885MAOB 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.