Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4069340 | 0.84 | KCNH2 (0.42) | KCNH2EHMT2EHMT1 | |
| SCHEMBL16986089 | 0.84 | KCNH2 (0.40) | KCNH2SLC2A1 | |
| SCHEMBL1223381 | 0.84 | KCNH2 (0.40) | KCNH2SLC2A1 | |
| SCHEMBL16986085 | 0.84 | KCNH2 (0.40) | KCNH2SLC2A1 | |
| SCHEMBL4068487 | 0.81 | EHMT2 (0.41) | KCNH2CYP8B1EHMT2EHMT1 | |
| SCHEMBL4069756 | 0.80 | KCNH2 (0.41) | KCNH2EHMT2EHMT1 | |
| Hydrochloric Acid SCHEMBL4069318 | 0.79 | EHMT2 (0.46) | KCNH2CYP8B1EHMT2EHMT1 | |
| SCHEMBL4068537 | 0.78 | CYP8B1 (0.41) | KCNH2CYP8B1EHMT2EHMT1 | |
| SCHEMBL1222834 | 0.77 | CYP2C19 (0.46) | KCNH2CYP8B1 | |
| SCHEMBL1222623 | 0.77 | NCF1 (0.57) | CYP8B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-22 | — | — | EP | disclosed |
| EP-1605938-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087145-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |