Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4069318 | 0.94 | EHMT2 (0.46) | KCNH2EHMT2EHMT1 | |
| SCHEMBL4068487 | 0.88 | EHMT2 (0.41) | KCNH2EHMT2EHMT1 | |
| SCHEMBL4069756 | 0.86 | KCNH2 (0.41) | KCNH2EHMT2EHMT1 | |
| SCHEMBL5780773 | 0.84 | KCNH2 (0.38) | KCNH2EHMT2EHMT1 | |
| SCHEMBL2955102 | 0.83 | CYP8B1 (0.39) | KCNH2 | |
| SCHEMBL2955854 | 0.82 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL4066839 | 0.81 | CYP8B1 (0.46) | KCNH2 | |
| SCHEMBL13948955 | 0.80 | ALDH1A1 (0.41) | KCNH2EHMT2EHMT1MAP4K4ALDH1A1 | |
| SCHEMBL4068537 | 0.80 | CYP8B1 (0.41) | KCNH2EHMT2EHMT1 | |
| SCHEMBL4062836 | 0.80 | KCNH2 (0.39) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-B1 | Antibacterial derivatives of napthydrin and quinoline | GLAXO GROUP LTD (GB) | 2009-02-11 | — | — | EP | disclosed |
| EP-1605938-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-22 | — | — | EP | disclosed |
| US-20060189601-A1 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
| EP-1605938-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087145-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189601-A1 | Antibacterial agents | NQO2, NRDC, IFNG | KCNH2 3365/4885EHMT2 4668/4885EHMT1 4661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.