Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30061109 | 1.00 | RARB (0.48) | RARBKAT8PPARAKDM4EPPARG | |
| SCHEMBL7744473 | 0.98 | RARB (0.46) | RARBKAT8PPARAKDM4EPPARG | |
| Ammonia Solution, Strong SCHEMBL27732570 | 0.88 | RARB (0.50) | RARBKAT8PPARAPPARGHCAR2 | |
| SCHEMBL7178039 | 0.84 | CNR2 (0.40) | RARBPPARAKDM4EPPARG | |
| SCHEMBL27963992 | 0.83 | RARB (0.49) | RARBKAT8PPARAPPARGHCAR2 | |
| SCHEMBL2536655 | 0.82 | KDM4E (0.50) | KDM4EPPARGHCAR2GABRPGABRD | |
| SCHEMBL27677228 | 0.81 | RARB (0.47) | RARBKAT8PPARAPPARGHCAR2 | |
| SCHEMBL8938795 | 0.79 | KDM4E (0.44) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2535736 | 0.78 | KDM4E (0.38) | RARBPPARAKDM4EGABRPGABRD | |
| SCHEMBL14645997 | 0.77 | ALDH1A1 (0.43) | RARBKAT8PPARAKDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983754-A | Method for the manufacture of dimethyl, octyl - or pentyl - para-aminobenzoic acid | BROMINE COMPOUNDS LTD. (IL) | 1991-01-08 | — | — | US | claimed |
| EP-2921518-B1 | ORGANOPOLYSILOXANE HAVING AMIDE GROUP, AND COSMETIC MATERIAL CONTAINING SAME | SHINETSU CHEMICAL CO (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-9890252-B2 | Silicone compound and cosmetic containing thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
| EP-3168255-B1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | SHINETSU CHEMICAL CO (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-20170137574-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-05-18 | — | — | US | disclosed |
| EP-3168255-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | Shin-Etsu Chemical Co., Ltd. (JP) | 2017-05-17 | — | — | EP | disclosed |
| EP-2921518-A1 | ORGANOPOLYSILOXANE HAVING AMIDE GROUP, AND COSMETIC MATERIAL CONTAINING SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2015-09-23 | — | — | EP | disclosed |
| EP-2280040-B1 | Organopolysiloxane having amide group, and cosmetic material containing same | SHINETSU CHEMICAL CO (JP) | 2015-04-15 | — | — | EP | disclosed |
| US-8912354-B2 | Organopolysiloxane and cosmetic containing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-12-16 | — | — | US | disclosed |
| US-8398964-B2 | Organopolysiloxane having amide group, and cosmetic material containing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| EP-2418236-B1 | Novel organopolysiloxane and cosmetic containing the same | SHINETSU CHEMICAL CO (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-20120040931-A1 | NOVEL ORGANOPOLYSILOXANE AND COSMETIC CONTAINING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-02-16 | — | — | US | disclosed |
| EP-2418236-A1 | Novel organopolysiloxane and cosmetic containing the same | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-20110027213-A1 | ORGANOPOLYSILOXANE HAVING AMIDE GROUP, AND COSMETIC MATERIAL CONTAINING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
| EP-2280040-A1 | Organopolysiloxane having amide group, and cosmetic material containing same | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-02-02 | — | — | EP | disclosed |
| EP-1291376-B1 | SILICONE POLYMER, SILICONE COMPOSITION, AND COSMETIC PREPARATION CONTAINING THE SAME | SHINETSU CHEMICAL CO (JP) | 2009-12-09 | — | — | EP | disclosed |
| EP-1291377-B1 | SILICONE COMPOUND AND COSMETIC PREPARATION | SHINETSU CHEMICAL CO (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-6984390-B2 | Silicone compound and cosmetic preparation | SHIN-ETSU CHEMICAL CO. LTD. (JP) | 2006-01-10 | — | — | US | disclosed |
| EP-1291376-A1 | SILICONE POLYMER, SILICONE COMPOSITION, AND COSMETIC PREPARATION CONTAINING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-03-12 | — | — | EP | disclosed |
| EP-1291377-A1 | SILICONE COMPOUND AND COSMETIC PREPARATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137574-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | CCND2, MRGPRX1, MRGPRX2 | RARB 908/4885KAT8 2602/4885PPARA 4286/4885 |
| US-20120040931-A1 | NOVEL ORGANOPOLYSILOXANE AND COSMETIC CONTAINING THE SAME | F12, FUCA1, H1-0 | RARB 1545/4885KAT8 851/4885PPARA 2871/4885 |
| US-20110027213-A1 | ORGANOPOLYSILOXANE HAVING AMIDE GROUP, AND COSMETIC MATERIAL CONTAINING SAME | HRH3, H1-3, HRH1 | RARB 669/4885KAT8 228/4885PPARA 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.