Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645957 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDKAT8PPARARARB | |
| SCHEMBL14645817 | 0.90 | KDM4E (0.42) | ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL14645962 | 0.86 | KDM4E (0.42) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL14645980 | 0.81 | ALDH1A1 (0.35) | ALDH1A1HPGDCSNK2BCSNK2A1PIP5K1A | |
| SCHEMBL14645847 | 0.78 | KDM4E (0.46) | KDM4EHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL14645991 | 0.77 | HTT (0.44) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL30061109 | 0.77 | RARB (0.48) | KAT8PPARARARBPPARGKDM4E | |
| SCHEMBL578085 | 0.77 | RARB (0.48) | KAT8PPARARARBPPARGKDM4E | |
| SCHEMBL8770841 | 0.77 | GABRP (0.48) | KAT8PPARARARBPPARGKDM4E | |
| SCHEMBL7744473 | 0.76 | RARB (0.46) | KAT8PPARARARBPPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729444-B1 | METHOD FOR MANUFACTURING 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| EP-2729444-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | Bayer Intellectual Property GmbH (DE) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013007603-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-17 | — | — | WO | disclosed |