Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.52 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423536 | 0.88 | MBTD1 (0.54) | HTR6MBTD1L3MBTL3 | |
| SCHEMBL3151906 | 0.87 | HTR6 (0.65) | HTR6MBTD1L3MBTL3OXTR | |
| SCHEMBL5783801 | 0.86 | HTR6 (0.54) | HTR6OXTR | |
| SCHEMBL5815985 | 0.86 | HTR6 (0.52) | HTR6OXTR | |
| SCHEMBL3146923 | 0.86 | HTR6 (0.66) | HTR6MBTD1L3MBTL3 | |
| SCHEMBL5809641 | 0.85 | HTR6 (0.54) | HTR6OXTR | |
| SCHEMBL5781541 | 0.84 | HTR6 (0.53) | HTR6OXTR | |
| SCHEMBL5785377 | 0.82 | HTR6 (0.64) | HTR6OXTR | |
| SCHEMBL3140363 | 0.81 | HTR6 (0.59) | HTR6OXTR | |
| SCHEMBL3148180 | 0.80 | MBTD1 (0.52) | HTR6MBTD1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-04-26 | — | — | EP | claimed |
| WO-2005014589-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2005-02-17 | — | — | WO | claimed |
| EP-1648886-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005014589-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2005-02-17 | — | — | WO | disclosed |