Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783801 | 0.89 | HTR6 (0.54) | HTR6OXTR | |
| SCHEMBL3143574 | 0.87 | HTR6 (0.62) | HTR6POLBMCOLN3OXTR | |
| SCHEMBL5780968 | 0.86 | HTR6 (0.52) | HTR6OXTR | |
| SCHEMBL3153469 | 0.86 | HTR6 (0.66) | HTR6POLBMCOLN3 | |
| SCHEMBL5809641 | 0.85 | HTR6 (0.54) | HTR6OXTR | |
| SCHEMBL5781541 | 0.82 | HTR6 (0.53) | HTR6OXTR | |
| SCHEMBL5430905 | 0.79 | PKM (0.50) | HTR6POLB | |
| SCHEMBL5785377 | 0.79 | HTR6 (0.64) | HTR6OXTR | |
| SCHEMBL3156992 | 0.78 | HTR6 (0.66) | HTR6OXTR | |
| SCHEMBL5439699 | 0.78 | ALDH1A1 (0.55) | HTR6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-04-26 | — | — | EP | claimed |
| WO-2005014589-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2005-02-17 | — | — | WO | claimed |