SCHEMBL578264

SCHEMBL578264

CCOP(=O)(OCC)c1ccc(F)cc1.O=P(O)(O)c1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TDP1 Q9NUW8 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
KDM4E B2RXH2 2/20 0.38
UTRN P46939 1/20 0.38
POLB P06746 1/20 0.37
MMP9 P14780 2/20 0.37
MMP1 P03956 1/20 0.37
MMP3 P08254 1/20 0.37
ADAM9 Q13443 1/20 0.37
CA2 P00918 2/20 0.36
CA4 P22748 2/20 0.36
CA5A P35218 2/20 0.36
LMNA P02545 3/20 0.36
GAA P10253 1/20 0.36
NR1I2 O75469 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL895236 0.91 ALDH1A1 (0.47) ALDH1A1TDP1KMT2AMEN1KDM4E
SCHEMBL4580177 0.83 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1KDM4ELMNA
SCHEMBL6829825 0.81 TDP1 (0.49) TDP1KMT2AMEN1POLBCA2
SCHEMBL12229756 0.80 ALDH1A1 (0.49) ALDH1A1KMT2AMEN1KDM4EUTRN
SCHEMBL1567573 0.79 CA2 (0.55) KMT2AMEN1CA2CA4CA5A
SCHEMBL8920392 0.79 LMNA (0.40) ALDH1A1KMT2AMEN1LMNACCNT1
SCHEMBL779299 0.76 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1KDM4EUTRN
SCHEMBL914688 0.76 MEN1 (0.47) ALDH1A1TDP1KMT2AMEN1POLB
SCHEMBL9407115 0.75 TDP1 (0.45) TDP1KMT2AMEN1POLBCA2
Phosphoric Acid SCHEMBL28091785 0.74 MEN1 (0.58) ALDH1A1KMT2AMEN1POLBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2417142-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS Georgia Tech Research Corporation (US) 2012-02-15 EP disclosed
WO-2010115854-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS GEORGIA TECH RESEARCH CORPORATION (US) 2010-10-14 WO disclosed