Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.55 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL262245 | 0.94 | — | — | |
| Bicarbonate SCHEMBL19511112 | 0.89 | CA4 (0.42) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL2496023 | 0.89 | CA4 (0.42) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL440938 | 0.89 | CA4 (0.42) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL10535508 | 0.89 | — | — | |
| Oxalic Acid SCHEMBL194221 | 0.89 | — | — | |
| Bicarbonate SCHEMBL4451318 | 0.89 | CA4 (0.42) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL578285 | 0.89 | CA4 (0.55) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL28420909 | 0.88 | CA4 (0.67) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL2275798 | 0.88 | CA4 (0.67) | CA4FAHD1MEN1LDHABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10053753-B2 | Aluminum-zinc plated steel sheet and method for producing the same | NIPPON STEEL & SUMIKIN COATED SHEET CORPORATION (JP) | 2018-08-21 | — | — | US | claimed |
| US-7438951-B2 | Aqueous super absorbent polymer and methods of use | H.B. FULLER LICENSING & FINANCING, INC. (US) | 2008-10-21 | — | — | US | claimed |
| US-20060035557-A1 | Aqueous super absorbent polymer and methods of use | H.B. FULLER COMPANY | 2006-02-16 | — | — | US | claimed |
| US-4025615-A | Antiperspirant complexes formed with alkali metal and ammonium zirconyl carbonates | ARMOUR PHARMACEUTICAL COMPANY (US) | 1977-05-24 | — | — | US | claimed |
| EP-4043610-B1 | METAL SURFACE-TREATING AGENT, AND METAL MATERIAL WITH COATING FILM AND METHOD FOR MANUFACTURING SAME | NIHON PARKERIZING (JP) | 2024-05-29 | — | — | EP | disclosed |
| US-11987888-B2 | Trivalent chromium chemical conversion treatment liquid for zinc or zinc alloy base and chemical conversion treatment method using the same | DIPSOL CHEMICALS CO., LTD. (JP) | 2024-05-21 | — | — | US | disclosed |
| CN-117460862-A | Method for producing surface-treated metal part and aqueous surface-treating agent for processing molded metal part | 日涂表面处理化工有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117321836-A | Cooling structure, battery device, and method for manufacturing cooling structure | 日本制铁株式会社 | 2023-12-29 | — | — | CN | disclosed |
| CN-116918141-A | Storage battery device | 日本制铁株式会社 | 2023-10-20 | — | — | CN | disclosed |
| US-20230304160-A1 | CHEMICAL CONVERSION TREATMENT SOLUTION, CHEMICAL CONVERSION TREATMENT METHOD IN WHICH SAME IS USED, AND CHEMICAL CONVERSION COATING | DIPSOL CHEMICALS CO., LTD. (JP) | 2023-09-28 | — | — | US | disclosed |
| WO-2023166858-A1 | HOT-DIP Al-Zn PLATED STEEL SHEET, METHOD FOR PRODUCING SAME, SURFACE-TREATED STEEL SHEET, AND COATED STEEL SHEET | ＪＦＥスチール株式会社 | 2023-09-07 | — | — | WO | disclosed |
| WO-2023132327-A1 | HOD DIPPED Al-Zn-Si-Mg COATED STEEL SHEET AND METHOD FOR PRODUCING SAME, SURFACE-TREATED STEEL SHEET AND METHOD FOR PRODUCING SAME, AND COATED STEEL SHEET AND METHOD FOR PRODUCING SAME | ＪＦＥスチール株式会社 | 2023-07-13 | — | — | WO | disclosed |
| US-5733666-A | REDUCE TANNIN STAINING | WAYNE PIGMENT CORP. (US) | 1998-03-31 | — | — | US | disclosed |
| US-5234870-A | ZIRCONIA SOL AND METHOD FOR PRODUCTION THEREOF | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0409282-A2 | Zirconia sol and method for production thereof | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| EP-0105128-B1 | AMORPHOUS ZIRCONIUM PHOSPHOSILICATE AND A PROCESS FOR PREPARING THE SAME | DAIICHI KIGENSO KAGAKU KOGYO CO. LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4526765-A | Mixing solutions of zirconium compound, phosphorus compound, silison compound to form slurry comprising oxides of phosphorus, zirconium, silicon, precipitating | DAIICHI KIGENSO KAGAKU KOGYO CO., LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0105128-A1 | Amorphous zirconium phosphosilicate and a process for preparing the same | DAIICHI KIGENSO KAGAKU KOGYO CO. LTD. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4025615-A | Antiperspirant complexes formed with alkali metal and ammonium zirconyl carbonates | ARMOUR PHARMACEUTICAL COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
| US-4021536-A | Magnesium-zirconium complexes useful as antiperspirants | ARMOUR PHARMACEUTICAL COMPANY (US) | 1977-05-03 | — | — | US | disclosed |