Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2496023 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL262245 | 0.94 | — | — | |
| Bicarbonate SCHEMBL4451318 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL19511112 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL10535508 | 0.89 | — | — | |
| Bicarbonate SCHEMBL578285 | 0.89 | CA4 (0.55) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL578313 | 0.89 | CA4 (0.55) | CA4CA1FAHD1LMNAMEN1 | |
| Acetic Acid SCHEMBL6340673 | 0.83 | CA1 (0.61) | CA4CA1FAHD1LMNABLM | |
| Bicarbonate SCHEMBL408953 | 0.82 | — | — | |
| Bicarbonate SCHEMBL17422 | 0.82 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705392-A1 | CURABLE LATEX COMPOSITIONS | Aquaspersions Ltd. (GB) | 2026-03-11 | — | — | EP | claimed |
| US-12540248-B2 | Metal surface-treating agent, and metal material with coating film and method for manufacturing same | NIHON PARKERIZING CO., LTD. (JP) | 2026-02-03 | — | — | US | claimed |
| WO-2025008484-A1 | CURABLE LATEX COMPOSITIONS | AQUASPERSIONS LTD. (GB) | 2025-01-09 | — | — | WO | claimed |
| EP-4488322-A1 | CURABLE LATEX COMPOSITIONS | Aquaspersions Ltd. (GB) | 2025-01-08 | — | — | EP | claimed |
| EP-4469509-A1 | A FOAMABLE POWDER-BASED COMPOSITION AND THE FOAMING METHOD THEREOF | Henkel AG & Co. KGaA (DE) | 2024-12-04 | — | — | EP | claimed |
| US-20240384133-A1 | FOAMABLE POWDER-BASED COMPOSITION AND THE FOAMING METHOD THEREOF | HENKEL AG & CO KGAA (DE) | 2024-11-21 | — | — | US | claimed |
| EP-3655473-B1 | DIELECTRIC HEATING OF FOAMABLE COMPOSITIONS | HENKEL AG & CO KGAA (DE) | 2024-09-11 | — | — | EP | claimed |
| CN-118613535-A | Foamable powder-based composition and foaming method thereof | 汉高股份有限及两合公司 | 2024-09-06 | — | — | CN | claimed |
| WO-2023142015-A1 | A FOAMABLE POWDER-BASED COMPOSITION AND THE FOAMING METHOD THEREOF | HENKEL AG & CO. KGAA (DE) | 2023-08-03 | — | — | WO | claimed |
| CN-116496545-A | Method for foaming a composition | 汉高股份有限及两合公司 | 2023-07-28 | — | — | CN | claimed |
| US-4400440-A | CROSSLING WITH AMMONIUM ZIRCONYL COMPLEX, NON-STICKING LAYERS | ALLIED PAPER INCORPORATED (US) | 1983-08-23 | — | — | US | claimed |
| US-4361669-A | Coating compositions comprising a reaction product of a dispersed _hydroxy-alkyl modified starch product and a hydrolyzed styrene maleic anhydride copolymer | CHAMPION INTERNATIONAL CORPORATION (US) | 1982-11-30 | — | — | US | claimed |
| EP-0016313-B1 | STABLE AQUEOUS COPPER ZIRCONIUM COMPLEX SALT SOLUTIONS, THEIR PREPARATION AND USE | MAGNESIUM ELEKTRON INC. (US) | 1982-09-22 | — | — | EP | claimed |
| US-4277292-A | AQUEOUS ACID SOLUTION OF TANNIN, ZIRCONIUM AND FLUORIDE IONS FOR COATING ALUMINUM CANS | CORAL CHEMICAL COMPANY (US) | 1981-07-07 | — | — | US | claimed |
| US-4274972-A | Process for preparing dilute aqueous copper zirconium ammonium carbonate solutions containing less than about 0.5% Cu and 1.5% ZrO2 | MAGNESIUM ELEKTRON INC. (US) | 1981-06-23 | — | — | US | claimed |
| EP-0016313-A1 | Stable aqueous copper zirconium complex salt solutions, their preparation and use | MAGNESIUM ELEKTRON INC. (US) | 1980-10-01 | — | — | EP | claimed |
| US-4105492-A | TREATED GLASS FIBERS | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1978-08-08 | — | — | US | claimed |
| US-4025615-A | Antiperspirant complexes formed with alkali metal and ammonium zirconyl carbonates | ARMOUR PHARMACEUTICAL COMPANY (US) | 1977-05-24 | — | — | US | claimed |
| US-4021536-A | Magnesium-zirconium complexes useful as antiperspirants | ARMOUR PHARMACEUTICAL COMPANY (US) | 1977-05-03 | — | — | US | claimed |
| US-3931085-A | POLYVALENT METAL COMPLEX | JOHNSON & JOHNSON (US) | 1976-01-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540248-B2 | Metal surface-treating agent, and metal material with coating film and method for manufacturing same | VMA21, CARM1, CROCC | CA4 31/4885CA1 6/4885FAHD1 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.