Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL440938 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL262245 | 0.94 | — | — | |
| Bicarbonate SCHEMBL4451318 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL19511112 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL10535508 | 0.89 | — | — | |
| Bicarbonate SCHEMBL578285 | 0.89 | CA4 (0.55) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL578313 | 0.89 | CA4 (0.55) | CA4CA1FAHD1LMNAMEN1 | |
| Acetic Acid SCHEMBL6340673 | 0.83 | CA1 (0.61) | CA4CA1FAHD1LMNABLM | |
| Bicarbonate SCHEMBL408953 | 0.82 | — | — | |
| Bicarbonate SCHEMBL17422 | 0.82 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880081-B1 | ACIDIC TREATMENT FLUIDS COMPRISING SCLEROGLUCAN AND/OR DIUTAN AND ASSOCIATED METHODS | HALLIBURTON ENERGY SERV INC (US) | 2013-03-06 | — | — | EP | claimed |
| EP-1292759-B1 | PROCESS FOR ALTERING THE RELATIVE PERMEABILITY OF A HYDROCARBON-BEARING FORMATION | TR OIL SERVICES LTD (GB) | 2004-09-22 | — | — | EP | claimed |
| JP-61044717-A | — | — | None | — | — | JP | disclosed |
| JP-4100921-A | — | — | None | — | — | JP | disclosed |
| JP-1101187-A | — | — | None | — | — | JP | disclosed |
| JP-4005077-A | — | — | None | — | — | JP | disclosed |
| JP-3054115-A | — | — | None | — | — | JP | disclosed |
| JP-3100012-A | — | — | None | — | — | JP | disclosed |
| WO-2022085721-A1 | ZN-BASED PLATED STEEL SHEET | 日本製鉄株式会社 | 2022-04-28 | — | — | WO | disclosed |
| EP-2808710-A1 | OPTICAL FILM | Konica Minolta Advanced Layers, Inc. (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-20140333996-A1 | OPTICAL FILM | Konica Minolta, Inc. (JP) | 2014-11-13 | — | — | US | disclosed |
| JP-H03100012-A | RESIN COMPOSITION AND ADHESIVE COMPOSITION | KURARAY CO LTD | 1991-04-25 | — | — | JP | disclosed |
| JP-H0354115-A | HIGH-PERFORMANCE ZIRCONIA SOL AND PRODUCTION THEREOF | NIPPON SHOKUBAI KAGAKU KOGYO CO LTD | 1991-03-08 | — | — | JP | disclosed |
| EP-0313412-A1 | Ceramic green sheet | NIPPON SHOKUBAI CO., LTD. (JP) | 1989-04-26 | — | — | EP | disclosed |
| JP-H01101187-A | THERMAL RECORDING MATERIAL | RICOH CO LTD | 1989-04-19 | — | — | JP | disclosed |
| US-4783224-A | Method for hydrophilic treatment of aluminum using an amphoteric polymer | NIHON PARKERIZING CO., LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| US-4581258-A | Photopolymer coated lithographic printing plate | PRINTING DEVELOPMENTS, INC. (US) | 1986-04-08 | — | — | US | disclosed |
| JP-S6144717-A | PRODUCTION OF FINE ZIRCONIA POWDER | NIPPON SHOKUBAI KAGAKU KOGYO CO LTD | 1986-03-04 | — | — | JP | disclosed |
| US-4522912-A | Photopolymer coated lithographic printing plate | PRINTING DEVELOPMENTS, INC. (US) | 1985-06-11 | — | — | US | disclosed |
| EP-0115433-A2 | Improved photopolymer coated lithographic printing plate | PRINTING DEVELOPMENTS INC (US) | 1984-08-08 | — | — | EP | disclosed |