Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5786106 | 0.72 | PNP (0.51) | TSHRUSP2HSD17B10RECQLPNP | |
| SCHEMBL9928535 | 0.70 | KDM4E (0.41) | USP2HSD17B10RECQLMAPTMEN1 | |
| SCHEMBL5804479 | 0.69 | CNR1 (0.45) | USP2PNPMAPTMEN1KMT2A | |
| SCHEMBL15293654 | 0.69 | PCSK9 (0.47) | TSHRUSP2MAPTMEN1KMT2A | |
| SCHEMBL6330436 | 0.65 | PNP (0.51) | TSHRUSP2HSD17B10RECQLPNP | |
| SCHEMBL571179 | 0.64 | PNP (0.55) | TSHRUSP2HSD17B10RECQLPNP | |
| SCHEMBL9566539 | 0.63 | PNP (0.60) | TSHRUSP2HSD17B10RECQLPNP | |
| SCHEMBL10861011 | 0.63 | PNP (0.62) | TSHRUSP2HSD17B10RECQLPNP | |
| SCHEMBL5784358 | 0.62 | PNP (0.48) | TSHRUSP2HSD17B10RECQLPNP | |
| SCHEMBL25432358 | 0.61 | MAPK8 (0.48) | PDE1BCNR2MAPK8ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270008-B1 | Fused tricyclic analogues of guanosine for treating tumors | YUNG SHIN PHARMACEUTICAL IND (TW) | 2006-07-12 | — | — | EP | disclosed |
| US-6887997-B2 | 9H-imidazo[1,2-a]purin-9-one compounds | YUNG SHIN PHARMACEUTICAL IND. CO., LTD. (TW) | 2005-05-03 | — | — | US | disclosed |
| US-20030105116-A1 | Fused tri-heterocyclic compounds | YUNG SHIN PHARMACEUTICAL IND. CO., LTD. (TW) | 2003-06-05 | — | — | US | disclosed |
| EP-1270008-A2 | Fused tricyclic analogues of guanosine for treating tumors | Yung Shin Pharmaceutical Ind. Co., Ltd. (TW) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105116-A1 | Fused tri-heterocyclic compounds | NR2E1, REL, RER1 | TSHR 123/4885USP2 3939/4885HSD17B10 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.