Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522309 | 0.70 | PNP (0.52) | PNPCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5783265 | 0.69 | TSHR (0.39) | PNPCYP1A2CYP3A4USP2ALDH1A1 | |
| SCHEMBL1753320 | 0.67 | CNR1 (0.44) | CNR1PNPYTHDC1PDE4AKDM4E | |
| SCHEMBL8165314 | 0.66 | PNP (0.56) | PNPCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8076818 | 0.65 | PNP (0.55) | PNPCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12786350 | 0.65 | YTHDC1 (0.69) | PNPYTHDC1CDK1PDE4APDE4B | |
| SCHEMBL6272417 | 0.65 | ALDH1A1 (0.66) | PNPCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17401396 | 0.65 | ENPP2 (0.67) | — | |
| SCHEMBL183057 | 0.65 | YTHDC1 (0.68) | PNPCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30898278 | 0.65 | YTHDC1 (0.68) | PNPCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270008-B1 | Fused tricyclic analogues of guanosine for treating tumors | YUNG SHIN PHARMACEUTICAL IND (TW) | 2006-07-12 | — | — | EP | disclosed |
| US-6887997-B2 | 9H-imidazo[1,2-a]purin-9-one compounds | YUNG SHIN PHARMACEUTICAL IND. CO., LTD. (TW) | 2005-05-03 | — | — | US | disclosed |
| US-20030105116-A1 | Fused tri-heterocyclic compounds | YUNG SHIN PHARMACEUTICAL IND. CO., LTD. (TW) | 2003-06-05 | — | — | US | disclosed |
| EP-1270008-A2 | Fused tricyclic analogues of guanosine for treating tumors | Yung Shin Pharmaceutical Ind. Co., Ltd. (TW) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105116-A1 | Fused tri-heterocyclic compounds | NR2E1, REL, RER1 | CNR1 54/4885PNP 3405/4885CYP1A2 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.