Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Carbamate SCHEMBL28618318 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNATDP1MAPK1 | |
| Benzyl Carbamate SCHEMBL11299634 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNATDP1MAPK1 | |
| Benzyl Carbamate SCHEMBL6992838 | 0.89 | ALDH1A1 (0.64) | ALDH1A1KMT2ALMNATDP1MAPK1 | |
| Benzyl Carbamate SCHEMBL8592590 | 0.89 | ALDH1A1 (0.64) | ALDH1A1KMT2ALMNATDP1MAPK1 | |
| Benzyl Carbamate SCHEMBL30227819 | 0.89 | ALDH1A1 (0.63) | ALDH1A1KMT2ALMNATDP1MAPK1 | |
| Benzyl Carbamate SCHEMBL10700633 | 0.89 | ALDH1A1 (0.63) | ALDH1A1KMT2ALMNATDP1MAPK1 | |
| Benzyl Carbamate SCHEMBL30227887 | 0.89 | ALDH1A1 (0.63) | ALDH1A1KMT2ALMNATDP1MAPK1 | |
| Benzyl Carbamate SCHEMBL1697 | 0.89 | ALDH1A1 (0.63) | ALDH1A1KMT2ALMNATDP1MAPK1 | |
| Benzyl Carbamate SCHEMBL28086051 | 0.87 | ALDH1A1 (0.62) | ALDH1A1KMT2ALMNATDP1MAPK1 | |
| Benzyl Carbamate SCHEMBL27278367 | 0.87 | ALDH1A1 (0.68) | ALDH1A1KMT2ALMNATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189591-A1 | Five-membered heterocyclic derivative | PTGS1, PTGIS, PTGS2 | ALDH1A1 251/4885KMT2A 4143/4885LMNA 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.