Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738397 | 0.85 | PDE1A (0.34) | — | |
| SCHEMBL6401061 | 0.84 | HTR2A (0.46) | HTR1ADRD2HTR2A | |
| SCHEMBL5738711 | 0.83 | MEN1 (0.39) | HTR1A | |
| SCHEMBL5738525 | 0.79 | HTR1A (0.44) | HTR1A | |
| SCHEMBL5739261 | 0.78 | HTR1A (0.40) | HTR1ADRD2HTR2A | |
| SCHEMBL6397678 | 0.75 | HTR2A (0.48) | HTR1ADRD2HTR2A | |
| SCHEMBL5740933 | 0.74 | HTR2A (0.38) | HTR1ADRD2HTR2A | |
| SCHEMBL5739172 | 0.74 | ADRA1D (0.40) | HTR1A | |
| SCHEMBL6400812 | 0.73 | HTR2A (0.47) | HTR1ADRD2HTR2A | |
| SCHEMBL5737988 | 0.71 | HTR1A (0.30) | HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697334-A1 | HETEROCYCLIC SUBSTITUTED INDANE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA | Warner-Lambert Company LLC (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005056540-A1 | HETEROCYCLIC SUBSTITUTED INDANE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-23 | — | — | WO | disclosed |