Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335744 | 0.86 | ADORA2A (0.43) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL6330871 | 0.86 | ADORA2A (0.43) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5789603 | 0.84 | HRH4 (0.42) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5789600 | 0.84 | BPTF (0.43) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5788681 | 0.81 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5788686 | 0.81 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5786652 | 0.80 | ALDH1A1 (0.64) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| Hydrochloric Acid SCHEMBL5787924 | 0.79 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL6331657 | 0.78 | ADORA2A (0.52) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5788569 | 0.78 | ADORA2A (0.52) | L3MBTL1ALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685115-A1 | NOVEL NOREPINEPHRINE REUPTAKE INHIBITORS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | Warner-Lambert Company LLC (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005042501-A1 | NOVEL NOREPINEPHRINE REUPTAKE INHIBITORS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY LLC (US) | 2005-05-12 | — | — | WO | disclosed |