Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775340 | 0.77 | NPC1 (0.77) | NPC1RAB9ANLRP3GABRG2GABRB3 | |
| SCHEMBL1270312 | 0.74 | GRM5 (0.55) | NPC1RAB9ANLRP3GRM5DDB1 | |
| SCHEMBL5201498 | 0.74 | NPC1 (0.41) | NPC1RAB9ANLRP3GABRG2GABRB3 | |
| SCHEMBL3262201 | 0.71 | NPC1 (0.46) | NPC1RAB9ANLRP3GRM5DDB1 | |
| SCHEMBL17279832 | 0.70 | RAB9A (0.67) | NPC1RAB9ANLRP3GABRG2GABRB3 | |
| SCHEMBL21430053 | 0.70 | NPC1 (0.61) | NPC1RAB9ANLRP3GRM5CNR1 | |
| SCHEMBL27836625 | 0.70 | NPC1 (0.61) | NPC1RAB9ANLRP3GABRG2GABRB3 | |
| SCHEMBL3504674 | 0.69 | NPC1 (0.47) | NPC1RAB9ANLRP3GRM5DDB1 | |
| SCHEMBL16039276 | 0.69 | PTGS1 (0.51) | NPC1RAB9ANLRP3KDM4EMEN1 | |
| SCHEMBL27784722 | 0.69 | NPC1 (0.55) | NPC1RAB9ANLRP3CNR1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343787-A1 | 6-PHENYL-PYRAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-17 | — | — | EP | claimed |
| WO-2002048151-A1 | 6-PHENYL-PYRAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | WO | claimed |
| US-20060258685-A1 | Substituted pyrazolopyrimidines, methods for the production thereof, use of the same for controlling pathogenic fungi, and agents containing said compounds | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-16 | — | — | US | disclosed |
| EP-1633755-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, METHODS FOR THE PRODUCTION THEREOF, USE OF THE SAME FOR CONTROLLING PATHOGENIC FUNGI, AND AGENTS CONTAINING SAID COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004106341-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, METHODS FOR THE PRODUCTION THEREOF, USE OF THE SAME FOR CONTROLLING PATHOGENIC FUNGI, AND AGENTS CONTAINING SAID COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-09 | — | — | WO | disclosed |
| EP-1343787-B1 | 6-PHENYL-PYRAZOLOPYRIMIDINES | BASF AG (DE) | 2004-11-10 | — | — | EP | disclosed |
| US-6730680-B2 | FUNGICIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI; AGRICULTURE, PLANT DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-04 | — | — | US | disclosed |
| US-6730680-B2 | FUNGICIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI; AGRICULTURE, PLANT DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-04 | — | — | US | disclosed |
| EP-1343787-A1 | 6-PHENYL-PYRAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-17 | — | — | EP | disclosed |
| EP-1343787-A1 | 6-PHENYL-PYRAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-20030158190-A1 | 6-phenyl-pyrazolopyrimidines | PEES KLAUS JUERGEN (DE) | 2003-08-21 | — | — | US | disclosed |
| US-20030158190-A1 | 6-phenyl-pyrazolopyrimidines | PEES KLAUS JUERGEN (DE) | 2003-08-21 | — | — | US | disclosed |
| US-6552026-B2 | Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-22 | — | — | US | disclosed |
| US-6552026-B2 | Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-22 | — | — | US | disclosed |
| WO-2002048151-A1 | 6-PHENYL-PYRAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | WO | disclosed |
| WO-2002048151-A1 | 6-PHENYL-PYRAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | WO | disclosed |
| US-20020049318-A1 | 6-phenyl-pyrazolopyrimidines | BASF CORPORATION (US) | 2002-04-25 | — | — | US | disclosed |
| US-20020049318-A1 | 6-phenyl-pyrazolopyrimidines | BASF CORPORATION (US) | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158190-A1 | 6-phenyl-pyrazolopyrimidines | CBR1, CBR3, CNPY2 | NPC1 2195/4885RAB9A 3914/4885NLRP3 829/4885 |
| US-20060258685-A1 | Substituted pyrazolopyrimidines, methods for the production thereof, use of the same for controlling pathogenic fungi, and agents containing said compounds | CBR1, CBR3, AKR7A2 | NPC1 583/4885RAB9A 4424/4885NLRP3 708/4885 |
| US-20020049318-A1 | 6-phenyl-pyrazolopyrimidines | CBR1, CBR3, CNPY2 | NPC1 2195/4885RAB9A 3914/4885NLRP3 829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.