Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.33 |
| ▸ | CPB1 | P15086 | 2/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929612 | 0.77 | KDM4E (0.35) | RAB9ANOTUMHPGDPHF8MEN1 | |
| SCHEMBL3504674 | 0.76 | NPC1 (0.47) | NPC1RAB9ANLRP3DDB1CRBN | |
| SCHEMBL10775340 | 0.73 | NPC1 (0.77) | NPC1RAB9ANLRP3DDB1CRBN | |
| SCHEMBL5785754 | 0.71 | NPC1 (0.50) | NPC1RAB9ANLRP3DDB1CRBN | |
| SCHEMBL4167465 | 0.71 | HPGDS (0.56) | NPC1RAB9ACYP3A4CYP2E1CYP2A6 | |
| SCHEMBL1270312 | 0.70 | GRM5 (0.55) | NPC1RAB9ANLRP3DDB1CRBN | |
| SCHEMBL5201498 | 0.70 | NPC1 (0.41) | NPC1RAB9ANLRP3DDB1CRBN | |
| SCHEMBL6018254 | 0.69 | MAPT (0.33) | NPC1RAB9APHF8MEN1ALDH1A1 | |
| SCHEMBL16039276 | 0.69 | PTGS1 (0.51) | NPC1RAB9ANLRP3HPGDMEN1 | |
| SCHEMBL3824076 | 0.69 | NPC1 (0.44) | NPC1RAB9ANLRP3DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208038-A1 | 6-(2-Fluorophenyl)-Triazolopyrimidines, Method for Producing Them, Their use for Controlling Parasitic Fungi and Agents Containing the Same | BASF AKTIENGESELLSCHAFT (DE) | 2007-09-06 | — | — | US | claimed |
| EP-1732927-A2 | 6-(2-FLUOROPHENYL)-TRIAZOLOPYRIMIDINES, METHOD FOR PRODUCING THEM, THEIR USE FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE SAME | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-20 | — | — | EP | claimed |
| WO-2005095404-A2 | 6-(2-FLUOROPHENYL)-TRIAZOLOPYRIMIDINES, METHOD FOR PRODUCING THEM, THEIR USE FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE SAME | BASF AKTIENGESELLSCHAFT (DE) | 2005-10-13 | — | — | WO | claimed |
| EP-0984919-B1 | PROCESS FOR THE PREPARATION OF ARYLMALONATES | BASF AG (DE) | 2003-01-22 | — | — | EP | claimed |
| US-20100160311-A1 | Fungicidal Azolopyrimidines, Process for Their Preparation and Their Use For Controlling Harmful Fungi, and Also Compositions Comprising Them | BASF SE (DE) | 2010-06-24 | — | — | US | disclosed |
| US-20100056371-A1 | Use of Azolopyrimidines for Controlling Phytopathogenic Harmful Fungi | BASF SE (DE) | 2010-03-04 | — | — | US | disclosed |
| EP-2117312-A1 | USE OF AZOLOPYRIMIDINES FOR FIGHTING PLANT PATHOGENIC FUNGI | BASF SE (DE) | 2009-11-18 | — | — | EP | disclosed |
| EP-2046794-A1 | FUNGICIDAL AZOLOPYRIMIDINES, METHODS FOR THE PRODUCTION THEREOF, USE THEREOF FOR CONTROLLING HARMFUL FUNGI, AND SUBSTANCES CONTAINING THE SAME | BASF SE (DE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008084027-A1 | USE OF AZOLOPYRIMIDINES FOR FIGHTING PLANT PATHOGENIC FUNGI | BASF SE (DE) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008006761-A1 | FUNGICIDAL AZOLOPYRIMIDINES, METHODS FOR THE PRODUCTION THEREOF, USE THEREOF FOR CONTROLLING HARMFUL FUNGI, AND SUBSTANCES CONTAINING THE SAME | BASF SE (DE) | 2008-01-17 | — | — | WO | disclosed |
| EP-1490372-B1 | FUNGICIDAL TRIAZOLOPYRIMIDINES, METHODS FOR PRODUCING THE SAME, USE THEREOF FOR COMBATING HARMFUL FUNGI AND AGENTS CONTAINING SAID SUBSTANCES | BASF AG (DE) | 2008-01-16 | — | — | EP | disclosed |
| US-20070111889-A1 | 6-(Aminocarbonyl-phenyl)triazolopyrimidines, methods for the production thereof, use thereof for controlling harmful fungi, and substances containing the same | BASF AKTIENGESELLSCHAFT (DE) | 2007-05-17 | — | — | US | disclosed |
| CN-1533393-A | Substituted (6-2-tolyl)-triazolopyrimidines as fungicides | �����ɷ� | 2004-09-29 | — | — | CN | disclosed |
| US-20040167136-A1 | Substituted 6-(2-methoxyphenyl) triazolopyrimides as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-26 | — | — | US | disclosed |
| US-20040162286-A1 | Substituted 6-(2-tolyl)-triazolopyrimidines as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-19 | — | — | US | disclosed |
| EP-1412359-A1 | SUBSTITUTED 6-(2-TOLYL)-TRIAZOLOPYRIMIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-04-28 | — | — | EP | disclosed |
| EP-1412356-A1 | SUBSTITUTED 6-(2-METHOXYPHENYL)TRIAZOLOPYRIMIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003008417-A9 | SUBSTITUTED 6-(2-TOLYL)-TRIAZOLOPYRIMIDINES AS FUNGICIDES | BASF AG (DE) | 2003-10-30 | — | — | WO | disclosed |
| WO-2003008417-A1 | SUBSTITUTED 6-(2-TOLYL)-TRIAZOLOPYRIMIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-30 | — | — | WO | disclosed |
| WO-2003008416-A1 | SUBSTITUTED 6-(2-METHOXYPHENYL) TRIAZOLOPYRIMIDES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056371-A1 | Use of Azolopyrimidines for Controlling Phytopathogenic Harmful Fungi | DPM1, TYMP, G6PD | NPC1 2575/4885RAB9A 3531/4885NLRP3 3077/4885 |
| US-20070208038-A1 | 6-(2-Fluorophenyl)-Triazolopyrimidines, Method for Producing Them, Their use for Controlling Parasitic Fungi and Agents Containing the Same | CBR1, CBR3, DPM1 | NPC1 762/4885RAB9A 2513/4885NLRP3 2722/4885 |
| US-20100160311-A1 | Fungicidal Azolopyrimidines, Process for Their Preparation and Their Use For Controlling Harmful Fungi, and Also Compositions Comprising Them | G6PD, CYP51A1, ERG28 | NPC1 2234/4885RAB9A 3120/4885NLRP3 648/4885 |
| US-20070111889-A1 | 6-(Aminocarbonyl-phenyl)triazolopyrimidines, methods for the production thereof, use thereof for controlling harmful fungi, and substances containing the same | CBR1, CBR3, DPM1 | NPC1 1967/4885RAB9A 3944/4885NLRP3 2538/4885 |
| US-20040162286-A1 | Substituted 6-(2-tolyl)-triazolopyrimidines as fungicides | CBR3, CBR1, TH | NPC1 2115/4885RAB9A 3028/4885NLRP3 1782/4885 |
| US-20040167136-A1 | Substituted 6-(2-methoxyphenyl) triazolopyrimides as fungicides | CBR3, CBR1, CNPY2 | NPC1 2036/4885RAB9A 3603/4885NLRP3 1141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.