SCHEMBL5786807

SCHEMBL5786807

CC(C)N(C(C)C)S(=O)(=O)NCCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.40
CA14 Q9ULX7 4/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
ECE1 P42892 3/20 0.37
ALDH1A1 P00352 3/20 0.36
PKLR P30613 1/20 0.35
FABP4 P15090 1/20 0.35
ATM Q13315 1/20 0.35
GABRP O00591 2/20 0.34
GABRD O14764 2/20 0.34
GABRA1 P14867 2/20 0.34
GABRB1 P18505 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA5 P31644 2/20 0.34
GABRA3 P34903 2/20 0.34
GABRA2 P47869 2/20 0.34
GABRB2 P47870 2/20 0.34
GABRA4 P48169 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5787487 0.79 TAS2R14 (0.38) CA12CA14CA7CA9ECE1
SCHEMBL5789288 0.79 ALDH1A1 (0.54) CA12CA14ALDH1A1PKLRFABP4
SCHEMBL5788836 0.78 CA12 (0.36) CA12CA14CA7CA9ECE1
SCHEMBL2842451 0.75 GRIA1 (0.56) CA12CA14CA7CA9ECE1
SCHEMBL7259224 0.72 CA12 (0.41) CA12CA14ECE1ALDH1A1FABP4
SCHEMBL21104550 0.71 GABRP (0.38) CA12CA14CA7CA9ECE1
SCHEMBL9266535 0.70 ALDH1A1 (0.44) CA12CA14ALDH1A1FABP4ATM
SCHEMBL26212048 0.69 ALDH1A1 (0.38) CA12CA14CA7CA9ECE1
SCHEMBL4877738 0.69 APEX1 (0.42) CA12CA14ECE1ALDH1A1FABP4
SCHEMBL26210415 0.68 ECE1 (0.38) CA12CA14CA7CA9ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622867-A1 N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS Almirall Prodesfarma, S.A. (ES) 2006-02-08 EP claimed
WO-2004099126-A1 N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN α4 ANTAGONISTS ALMIRALL PRODESFARMA SA (ES) 2004-11-18 WO claimed
EP-1622867-A1 N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS Almirall Prodesfarma, S.A. (ES) 2006-02-08 EP disclosed
WO-2004099126-A1 N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN α4 ANTAGONISTS ALMIRALL PRODESFARMA SA (ES) 2004-11-18 WO disclosed