Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cyclopentanamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OAT | P04181 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL578785 | 0.97 | CES2 (0.43) | THRBALDH1A1MMP8MMP1CES2 | |
| Cyclooctanamine SCHEMBL11193013 | 0.97 | CES2 (0.43) | THRBALDH1A1MMP8MMP1CES2 | |
| Cycloheptanamine SCHEMBL720218 | 0.97 | CES2 (0.43) | THRBALDH1A1MMP8MMP1CES2 | |
| Cyclohexylamine SCHEMBL974340 | 0.97 | CES2 (0.43) | THRBALDH1A1MMP8MMP1CES2 | |
| Cyclohexylamine SCHEMBL27712727 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MMP8MMP1CES2CES1 | |
| Cyclopentanamine SCHEMBL3875980 | 0.90 | ACHE (0.44) | THRBMEN1KMT2AALDH1A1MMP8 | |
| Bicarbonate SCHEMBL578685 | 0.90 | — | — | |
| Bicarbonate SCHEMBL7136153 | 0.89 | GABRR1 (0.42) | GABRR1LMNAOAT | |
| Bicarbonate SCHEMBL7136582 | 0.89 | GABRR1 (0.42) | GABRR1LMNAOAT | |
| Bicarbonate SCHEMBL1702507 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169403-B9 | ORAL PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY BOWEL DISEASES | PROTAGONIST THERAPEUTICS INC (US) | 2024-07-03 | — | — | EP | claimed |
| EP-3169403-B1 | ORAL PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY BOWEL DISEASES | PROTAGONIST THERAPEUTICS INC (US) | 2024-02-14 | — | — | EP | claimed |
| EP-1765408-B1 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK AS (DK) | 2015-12-09 | — | — | EP | claimed |
| EP-2289560-B1 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK AS (DK) | 2015-04-22 | — | — | EP | claimed |
| EP-2462147-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2014-11-12 | — | — | EP | claimed |
| EP-2516009-B1 | SUBSTITUTED ISOQUINOLINONES AND QUINAZOLINONES | NOVARTIS AG (CH) | 2014-09-24 | — | — | EP | claimed |
| EP-2231701-B1 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES | CADILA HEALTHCARE LTD (IN) | 2012-04-18 | — | — | EP | claimed |
| EP-1883451-B9 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON INC (CA) | 2011-02-09 | — | — | EP | claimed |
| EP-1883451-B1 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON INC (CA) | 2010-11-24 | — | — | EP | claimed |
| EP-1006122-B1 | PHENETHYLAMINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-12-03 | — | — | EP | claimed |
| EP-1257575-B1 | RADIOLABELED VASOACTIVE INTESTINAL PEPTIDE ANALOGS FOR DIAGNOSIS AND RADIOTHERAPY | DABUR RES FOUNDATION (IN) | 2007-02-28 | — | — | EP | claimed |
| EP-1337551-B1 | SUBSTANCE P ANALOGS FOR THE TREATMENT OF CANCER | DABUR PHARMA LTD (IN) | 2007-01-03 | — | — | EP | claimed |
| EP-1165099-B1 | ANGIOTENSIN II AND ANALOGS THEREOF FOR LIMITING SCAR AND ADHESION FORMATION | UNIV SOUTHERN CALIFORNIA (US) | 2006-08-09 | — | — | EP | claimed |
| EP-1257576-B1 | VASOACTIVE INTESTINAL PEPTIDE ANALOGS | DABUR RES FOUNDATION (IN) | 2004-09-15 | — | — | EP | claimed |
| EP-0606881-B1 | Cyclic pentapeptides having a beta-turn and a gamma-turn | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0245961-B1 | ACID GAS SCRUBBING COMPOSITION AND PROCESS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-04-03 | — | — | EP | claimed |
| EP-2708569-B1 | TRANSPARENT POLYAMIDE-IMIDES | EMS PATENT AG (CH) | 2018-05-23 | — | — | EP | disclosed |
| EP-2708569-A1 | Transparent polyamidimide | EMS-PATENT AG (CH) | 2014-03-19 | — | — | EP | disclosed |
| EP-0284942-A2 | Amino-acid derivatives | MERCK PATENT GmbH (DE) | 1988-10-05 | — | — | EP | disclosed |
| EP-0068373-A1 | Schiff bases of aminocycloalcanecarboxylic esters, preparation thereof and use thereof as intermediate products | BASF Aktiengesellschaft (DE) | 1983-01-05 | — | — | EP | disclosed |