SCHEMBL578733

SCHEMBL578733

Cc1ccc(S(=O)(=O)OCCOCCOCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
LMNA P02545 2/20 0.46
AR P10275 1/20 0.45
ATM Q13315 2/20 0.45
MAPT P10636 2/20 0.45
CA9 Q16790 2/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
CA12 O43570 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MCHR1 Q99705 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
PIR O00625 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267237 1.00 ALDH1A1 (0.50) ALDH1A1GAAPKMLMNAAR
SCHEMBL18428696 1.00 ALDH1A1 (0.50) ALDH1A1GAAPKMLMNAAR
SCHEMBL20958124 1.00 ALDH1A1 (0.50) ALDH1A1GAAPKMLMNAAR
SCHEMBL1219330 1.00 ALDH1A1 (0.50) ALDH1A1GAAPKMLMNAAR
SCHEMBL12595169 1.00 ALDH1A1 (0.50) ALDH1A1GAAPKMLMNAAR
SCHEMBL30869939 1.00 ALDH1A1 (0.50) ALDH1A1GAAPKMLMNAAR
SCHEMBL578328 0.98 ALDH1A1 (0.51) ALDH1A1GAAPKMLMNAAR
SCHEMBL30380217 0.96 ALDH1A1 (0.47) ALDH1A1GAAPKMLMNAAR
SCHEMBL21405231 0.96 ALDH1A1 (0.47) ALDH1A1GAAPKMLMNAAR
SCHEMBL30380528 0.96 ALDH1A1 (0.47) ALDH1A1GAAPKMLMNAAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891415-A Preparation method of 2- [2- (2-aminoethoxy) ethoxy ] ethanol 安徽昊帆生物有限公司 2023-10-17 CN claimed
US-12577255-B2 MDM2-based modulators of proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-03-17 US disclosed
US-12552783-B2 Modulators of proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-17 US disclosed
US-12310975-B2 Modulators of BCL6 proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2025-05-27 US disclosed
US-20250114461-A1 CDK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-04-10 US disclosed
US-20250032623-A1 HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. 2025-01-30 US disclosed
US-12202829-B2 Heterocyclic compound FIMECS, INC. (JP) 2025-01-21 US disclosed
US-20250019371-A1 SMALL-MOLECULAR INHIBITORS FOR THE BETA-CATENIN/ B-CELL LYMPHOMA 9 PROTEIN-PROTEIN INTERACTION H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2025-01-16 US disclosed
US-12097261-B2 CDK2 degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2024-09-24 US disclosed
US-20240197899-A1 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2024-06-20 US disclosed
EP-2418203-A1 CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP Daiichi Sankyo Company, Limited (JP) 2012-02-15 EP disclosed
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12310975-B2 Modulators of BCL6 proteolysis and associated methods of use BCL6, BCL6B, BCL3 ALDH1A1 3306/4885GAA 1577/4885PKM 3895/4885
US-12577255-B2 MDM2-based modulators of proteolysis and associated methods of use MDM2, UBR4, UBE3A ALDH1A1 3895/4885GAA 1755/4885PKM 2846/4885
US-12097261-B2 CDK2 degraders and uses thereof CDK2, CDK20, CDK1 ALDH1A1 3701/4885GAA 2132/4885PKM 1392/4885
US-20250114461-A1 CDK2 DEGRADERS AND USES THEREOF CDK2, CDK20, CDK1 ALDH1A1 3701/4885GAA 2132/4885PKM 1392/4885
US-20240197899-A1 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF AADAC, BRD4, IDO2 ALDH1A1 148/4885GAA 2659/4885PKM 2007/4885
US-20250032623-A1 HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE AURKB, CDK9, AURKA ALDH1A1 4001/4885GAA 2482/4885PKM 1343/4885
US-12552783-B2 Modulators of proteolysis and associated methods of use CRBN, ADRM1, MDM2 ALDH1A1 3965/4885GAA 1317/4885PKM 2525/4885
US-20250019371-A1 SMALL-MOLECULAR INHIBITORS FOR THE BETA-CATENIN/ B-CELL LYMPHOMA 9 PROTEIN-PROTEIN INTERACTION BCL9, BCL9L, BCL6 ALDH1A1 3965/4885GAA 3528/4885PKM 4183/4885
US-12202829-B2 Heterocyclic compound XIAP, BIRC5, BIRC3 ALDH1A1 2510/4885GAA 1957/4885PKM 4131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.