Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575500 | 0.79 | — | — | |
| SCHEMBL14611589 | 0.79 | ALDH1A1 (0.33) | ALOX15ALDH1A1TSHR | |
| SCHEMBL6200371 | 0.77 | ACHE (0.30) | — | |
| SCHEMBL2479329 | 0.77 | FFAR3 (0.38) | ALOX15ALDH1A1TSHR | |
| SCHEMBL984906 | 0.75 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL2679117 | 0.74 | — | — | |
| SCHEMBL8205181 | 0.73 | ALDH1A1 (0.41) | LMNAALDH1A1KMT2A | |
| SCHEMBL27869033 | 0.70 | — | — | |
| SCHEMBL28394739 | 0.70 | LMNA (0.33) | LMNAALOX15BLMPMP22 | |
| Hydrochloric Acid SCHEMBL16666609 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406447-A | The crystal form of pyrrolopyridine compounds | 基因泰克公司 | 2017-11-28 | — | — | CN | disclosed |
| EP-1385524-A4 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO KG (DE) | 2006-02-01 | — | — | EP | disclosed |
| EP-1385524-A1 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | Abbott GmbH & Co. KG (DE) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002080926-A1 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO. KG (DE) | 2002-10-17 | — | — | WO | disclosed |