SCHEMBL578770

SCHEMBL578770

[c]1cc2ccc3ccccc3c2c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
HSD17B10 Q99714 5/20 0.44
CYP2A6 P11509 5/20 0.44
TSHR P16473 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
HPRT1 P00492 1/20 0.41
HPGD P15428 3/20 0.39
HIF1A Q16665 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
RAB9A P51151 1/20 0.39
CASP7 P55210 1/20 0.39
ATM Q13315 1/20 0.39
CYP1A2 P05177 4/20 0.38
CYP1B1 Q16678 1/20 0.38
THRB P10828 1/20 0.38
NQO2 P16083 1/20 0.35
PTPN22 Q9Y2R2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22518639 0.94 HSD17B10 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL534875 0.90 HPRT1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL17200851 0.87 ALDH1A1 (0.33) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL144610 0.81 HSD17B10 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL18318769 0.79 CYP2A6 (0.47) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL6537252 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL25131 0.78 ALDH1A1 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL845365 0.78 ALDH1A1 (0.42) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL2452867 0.76 ALDH1A1 (0.61) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL9957851 0.76 TNF (0.38) ALDH1A1HSD17B10TSHRTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9812661-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2017-11-07 US claimed
EP-2418707-B1 ORGANIC ELECTROLUMINESCENT ELEMENT AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2014-11-26 EP claimed
US-20120119196-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 US claimed
EP-2418707-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd. (JP) 2012-02-15 EP claimed
US-8039127-B2 Organic electroluminescence device and material for organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2011-10-18 US claimed
US-8039129-B2 Organic electroluminescence device and material for organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2011-10-18 US claimed
US-20100258791-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US claimed
US-20100253211-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-07 US claimed
EP-3389107-B1 ORGANIC EL LIGHT EMITTING APPARATUS AND ELECTRONIC INSTRUMENT IDEMITSU KOSAN CO (JP) 2024-06-05 EP disclosed
CN-114656481-A Organic material and application thereof 北京燕化集联光电技术有限公司 2022-06-24 CN disclosed
US-11322711-B2 Organic EL light emitting apparatus and electronic instrument IDEMITSU KOSAN CO., LTD. (JP) 2022-05-03 US disclosed
US-10941144-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2021-03-09 US disclosed
US-20210043866-A1 ORGANIC EL LIGHT EMITTING APPARATUS AND ELECTRONIC INSTRUMENT IDEMITSU KOSAN CO., LTD. (JP) 2021-02-11 US disclosed
US-10854838-B2 Organic EL light emitting apparatus and electronic instrument IDEMITSU KOSAN CO., LTD. (JP) 2020-12-01 US disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed
US-20100301318-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-12-02 US disclosed
US-20100301319-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-12-02 US disclosed
US-20100258791-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed
US-20100253211-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-07 US disclosed
US-20100253211-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE AOC1, EBPL, CYBA ALDH1A1 277/4885HSD17B10 3421/4885CYP2A6 2102/4885
US-20100258791-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, LEF1, LIMK1 ALDH1A1 222/4885HSD17B10 3305/4885CYP2A6 2640/4885
US-10941144-B2 Organic electroluminescence device and electronic device L1CAM, ESR1, CHRM1 ALDH1A1 83/4885HSD17B10 2792/4885CYP2A6 2172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.