Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7692947 | 0.87 | — | — | |
| Hydrogen Peroxide SCHEMBL28178154 | 0.87 | — | — | |
| Acetic Acid SCHEMBL6288674 | 0.83 | FFAR3 (0.58) | CA2CA5ACA5BKDM4ECYP3A4 | |
| Acetic Acid SCHEMBL440498 | 0.83 | — | — | |
| Oxalic Acid SCHEMBL3413023 | 0.82 | CA5A (0.60) | CA2CA5ACA5BKDM4EFFAR3 | |
| Hydrogen Peroxide SCHEMBL28116494 | 0.82 | — | — | |
| SCHEMBL246838 | 0.82 | CA2 (0.58) | CA2CA5ACA5BKDM4ECYP3A4 | |
| SCHEMBL105 | 0.82 | — | — | |
| SCHEMBL25599 | 0.82 | CA2 (0.58) | CA2CA5ACA5BKDM4ECYP3A4 | |
| SCHEMBL8596055 | 0.82 | CA2 (0.58) | CA2CA5ACA5BKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3114109-A1 | INHIBITORS OF HISTONE LYSINE SPECIFIC DEMETHYLASE (LSD1) AND HISTONE DEACETYLASES (HDACS) | The Johns Hopkins University (US) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015134973-A1 | INHIBITORS OF HISTONE LYSINE SPECIFIC DEMETHYLASE (LSD1) AND HISTONE DEACETYLASES (HDACS) | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-09-11 | — | — | WO | disclosed |
| EP-1650200-A1 | SULFONATE COMPOUND AND FLUORESCENT PROBE USING THE SAME | Osaka Industrial Promotion Organization (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-0375349-B1 | Phosphinic acid substituted steroids as inhibitors of steroid 5alpha-reductase | SMITHKLINE BEECHAM CORP (US) | 1994-08-31 | — | — | EP | disclosed |
| EP-0375349-A1 | Phosphinic acid substituted steroids as inhibitors of steroid 5alpha-reductase | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0007779-B1 | METHOD OF INCREASING THE VISCOSITY OF A THERMOSET COMPOSITION AND SHAPED ARTICLES MADE FROM THIS COMPOSITION | ICI AMERICAS INC. (US) | 1983-07-20 | — | — | EP | disclosed |
| US-4296215-A | POLYISOLYANATE TRIMERIZATION, VINYL URETHANE, UNSATURATED POLYESTER CURABLE BLEND | ICI AMERICAS INC. (US) | 1981-10-20 | — | — | US | disclosed |
| EP-0000658-B1 | PROCESS FOR PREPARING ETHYLENICALLY UNSATURATED ISOCYANURATES | ICI AMERICAS INC. (US) | 1981-09-02 | — | — | EP | disclosed |
| EP-0007779-A1 | Method of increasing the viscosity of a thermoset composition and shaped articles made from this composition | ICI AMERICAS INC. (US) | 1980-02-06 | — | — | EP | disclosed |
| EP-0000658-A1 | Process for preparing ethylenically unsaturated isocyanurates | ICI AMERICAS INC. (US) | 1979-02-07 | — | — | EP | disclosed |
| US-4128537-A | COPPER COMPOUND CATALYST, TRIMERIZATION | ICI AMERICAS INC. (US) | 1978-12-05 | — | — | US | disclosed |