Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL440498 | 1.00 | — | — | |
| Sulfuric Acid SCHEMBL6727153 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNCA2KDM4E | |
| Acetic Acid SCHEMBL8375833 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNCA2KDM4E | |
| Acetone SCHEMBL2586373 | 0.87 | — | — | |
| Sulfuric Acid SCHEMBL7640374 | 0.87 | FFAR3 (0.64) | FFAR3LCKFYNCA2KDM4E | |
| Sulfuric Acid SCHEMBL164130 | 0.87 | FFAR3 (0.64) | FFAR3LCKFYNCA2KDM4E | |
| Sulfuric Acid SCHEMBL282882 | 0.87 | — | — | |
| Bicarbonate SCHEMBL7692947 | 0.87 | — | — | |
| Sulfuric Acid SCHEMBL10378486 | 0.87 | FFAR3 (0.64) | FFAR3LCKFYNCA2KDM4E | |
| Sulfuric Acid SCHEMBL28072247 | 0.87 | FFAR3 (0.64) | FFAR3LCKFYNCA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030113284-A1 | Use of DHEA derivatives on keratinous substances | L'OREAL (FR) | 2003-06-19 | — | — | US | claimed |
| EP-1306081-A1 | Cosmetic use of DHEA-derivatives | L'OREAL (FR) | 2003-05-02 | — | — | EP | claimed |
| US-11746311-B2 | Granulate for detergent composition comprising nitrogen-containing builders | RECKITT BENCKISER FINISH B.V. (NL) | 2023-09-05 | — | — | US | disclosed |
| US-20210340470-A1 | GRANULATE FOR DETERGENT COMPOSITION COMPRISING NITROGEN-CONTAINING BUILDERS | RECKITT BENCKISER FINISH B.V. (NL) | 2021-11-04 | — | — | US | disclosed |
| EP-3850071-A1 | GRANULATE FOR DETERGENT COMPOSITION | Reckitt Benckiser Finish B.V. (NL) | 2021-07-21 | — | — | EP | disclosed |
| WO-2020053132-A1 | GRANULATE FOR DETERGENT COMPOSITION | RECKITT BENCKISER FINISH B.V. (NL) | 2020-03-19 | — | — | WO | disclosed |
| US-6964954-B2 | Use of DHEA derivatives on keratinous substances | L'OREAL (FR) | 2005-11-15 | — | — | US | disclosed |
| US-20030113284-A1 | Use of DHEA derivatives on keratinous substances | L'OREAL (FR) | 2003-06-19 | — | — | US | disclosed |
| EP-1306081-A1 | Cosmetic use of DHEA-derivatives | L'OREAL (FR) | 2003-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030113284-A1 | Use of DHEA derivatives on keratinous substances | SHBG, CYP21A2, NR5A1 | FFAR3 3696/4885LCK 3361/4885FYN 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.